Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 2/20 | 0.65 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.43 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.43 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GABRP | O00591 | 1/20 | 0.30 |
| ▸ | GABRD | O14764 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28684376 | 1.00 | TRIM24 (0.65) | TRIM24TRIM33ALDH1A1CRBNFKBP5 | |
| Cyclohexanone SCHEMBL2304082 | 1.00 | TRIM24 (0.65) | TRIM24TRIM33ALDH1A1CRBNFKBP5 | |
| SCHEMBL29018335 | 1.00 | TRIM24 (0.65) | TRIM24TRIM33ALDH1A1CRBNFKBP5 | |
| Cycloheptanone SCHEMBL16014570 | 1.00 | TRIM24 (0.65) | TRIM24TRIM33ALDH1A1CRBNFKBP5 | |
| SCHEMBL7352869 | 1.00 | TRIM24 (0.65) | TRIM24TRIM33ALDH1A1CRBNFKBP5 | |
| SCHEMBL22319296 | 1.00 | TRIM24 (0.65) | TRIM24TRIM33ALDH1A1CRBNFKBP5 | |
| SCHEMBL23804316 | 1.00 | TRIM24 (0.65) | TRIM24TRIM33ALDH1A1CRBNFKBP5 | |
| SCHEMBL7328823 | 1.00 | TRIM24 (0.65) | TRIM24TRIM33ALDH1A1CRBNFKBP5 | |
| SCHEMBL22319280 | 1.00 | TRIM24 (0.65) | TRIM24TRIM33ALDH1A1CRBNFKBP5 | |
| SCHEMBL29121495 | 1.00 | TRIM24 (0.65) | TRIM24TRIM33ALDH1A1CRBNFKBP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0153055-B1 | SATURATED TRICYCLIC NITROGEN-CONTAINING DIONES, A PROCESS FOR PREPARING THE SAME AND A PHARMACEUTICAL COMPOSITION CONTAINING THE COMPOUNDS | WARNER-LAMBERT COMPANY (US) | 1988-11-23 | — | — | EP | disclosed |
| US-4619937-A | Saturated bicyclic lactam acids and derivatives as cognition activators | WARNER-LAMBERT COMPANY (US) | 1986-10-28 | — | — | US | disclosed |
| US-4562195-A | Reversing amnesia with saturated tricyclic nitrogen-containing diones | WARNER-LAMBERT COMPANY (US) | 1985-12-31 | — | — | US | disclosed |
| EP-0153055-A1 | Saturated tricyclic nitrogen-containing diones, a process for preparing the same and a pharmaceutical composition containing the compounds | WARNER-LAMBERT COMPANY (US) | 1985-08-28 | — | — | EP | disclosed |
| EP-0151541-A2 | Saturated bicyclic lactam acids, their derivatives, a process for preparing the compounds and a pharmaceutical composition comprising the compounds | WARNER-LAMBERT COMPANY (US) | 1985-08-14 | — | — | EP | disclosed |
| US-4057559-A | ANTIINFLAMMATORY AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-11-08 | — | — | US | disclosed |