Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 2/20 | 0.65 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.43 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.43 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GABRP | O00591 | 1/20 | 0.30 |
| ▸ | GABRD | O14764 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28684376 | 1.00 | TRIM24 (0.65) | TRIM24TRIM33ALDH1A1CRBNFKBP5 | |
| SCHEMBL29018335 | 1.00 | TRIM24 (0.65) | TRIM24TRIM33ALDH1A1CRBNFKBP5 | |
| Cycloheptanone SCHEMBL16014570 | 1.00 | TRIM24 (0.65) | TRIM24TRIM33ALDH1A1CRBNFKBP5 | |
| SCHEMBL7352869 | 1.00 | TRIM24 (0.65) | TRIM24TRIM33ALDH1A1CRBNFKBP5 | |
| SCHEMBL22319296 | 1.00 | TRIM24 (0.65) | TRIM24TRIM33ALDH1A1CRBNFKBP5 | |
| SCHEMBL23804316 | 1.00 | TRIM24 (0.65) | TRIM24TRIM33ALDH1A1CRBNFKBP5 | |
| Cycloheptanone SCHEMBL10636618 | 1.00 | TRIM24 (0.65) | TRIM24TRIM33ALDH1A1CRBNFKBP5 | |
| SCHEMBL7328823 | 1.00 | TRIM24 (0.65) | TRIM24TRIM33ALDH1A1CRBNFKBP5 | |
| SCHEMBL22319280 | 1.00 | TRIM24 (0.65) | TRIM24TRIM33ALDH1A1CRBNFKBP5 | |
| SCHEMBL29121495 | 1.00 | TRIM24 (0.65) | TRIM24TRIM33ALDH1A1CRBNFKBP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110263564-A1 | PYRIDINE, BICYCLIC PYRIDINE AND RELATED ANALOGS AS SIRTUIN MODULATORS | SIRTRIS PHARMACEUTICALS, INC. (US) | 2011-10-27 | — | — | US | disclosed |
| EP-2350051-A1 | PYRIDINE, BICYCLIC PYRIDINE AND RELATED ANALOGS AS SIRTUIN MODULATORS | Sirtris Pharmaceuticals, Inc. (US) | 2011-08-03 | — | — | EP | disclosed |
| US-7776582-B2 | for gas chromatography; identifying an optically enhanced chiral ionic liquid (OCIL) for enantiomeric resolution | SIGMA-ALDRICH CO. (US) | 2010-08-17 | — | — | US | disclosed |
| WO-2010056549-A1 | PYRIDINE, BICYCLIC PYRIDINE AND RELATED ANALOGS AS SIRTUIN MODULATORS | SIRTRIS PHARMACEUTICALS, INC. (US) | 2010-05-20 | — | — | WO | disclosed |
| US-20090145197-A1 | Optically Enhanced Chiral Ionic Liquids | SIGMA-ALDRICH CO. NEWCO INC. | 2009-06-11 | — | — | US | disclosed |
| EP-1765781-A2 | OPTICALLY ENHANCED CHIRAL IONIC LIQUIDS | Sigma-Aldrich Co. (US) | 2007-03-28 | — | — | EP | disclosed |
| WO-2006017148-A2 | OPTICALLY ENHANCED CHIRAL IONIC LIQUIDS | SIGMA-ALRICH CO. (US) | 2006-02-16 | — | — | WO | disclosed |
| US-20060014955-A1 | Optically enhanced chiral ionic liquids | ADVANCED SEPARATION TECHNOLOGIES INC. (US) | 2006-01-19 | — | — | US | disclosed |
| EP-1123299-A1 | PREPARATION OF BIS ARYL CYCLOPENTADIENYL GROUP IVA METAL DIHALIDES | BOULDER SCIENTIFIC COMPANY (US) | 2001-08-16 | — | — | EP | disclosed |
| WO-2001014389-A1 | PREPARATION OF BIS ARYL CYCLOPENTADIENYL GROUP IVA METAL DIHALIDES | BOULDER SCIENTIFIC COMPANY (US) | 2001-03-01 | — | — | WO | disclosed |
| US-5268386-A | Containing a carboxy group | SHIONOGI & CO., LTD. (JP) | 1993-12-07 | — | — | US | disclosed |
| EP-0415566-A1 | Heterocyclic compounds, processes for producing them and pharmaceutical compositions comprising them | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1991-03-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060014955-A1 | Optically enhanced chiral ionic liquids | GCG, INF2, ELOVL3 | TRIM24 3593/4885TRIM33 4534/4885ALDH1A1 3108/4885 |
| US-20110263564-A1 | PYRIDINE, BICYCLIC PYRIDINE AND RELATED ANALOGS AS SIRTUIN MODULATORS | SIRT1, SIRT3, SIRT6 | TRIM24 1069/4885TRIM33 2080/4885ALDH1A1 2062/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.