Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CFTR | P13569 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.43 |
| ▸ | F2RL1 | P55085 | 2/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | JUN | P05412 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | IAPP | P10997 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7264603 | 0.88 | CFTR (0.49) | TSHRCFTRALDH1A1TAAR1SMN1; SMN2 | |
| SCHEMBL14158807 | 0.86 | CFTR (0.48) | TSHRCFTRALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL30695756 | 0.85 | BID (0.47) | CFTRALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL15995365 | 0.85 | BID (0.47) | CFTRALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL27967827 | 0.85 | BID (0.47) | CFTRALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL14158501 | 0.85 | BID (0.47) | CFTRALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9174929 | 0.84 | TAAR1 (0.58) | TSHRCFTRALDH1A1TAAR1F2RL1 | |
| SCHEMBL69199 | 0.84 | HPGD (0.41) | ALDH1A1JUNGAAIAPPMEN1 | |
| SCHEMBL2136831 | 0.83 | TSHR (0.50) | TSHRALDH1A1TAAR1AKR1B1SMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL14719474 | 0.82 | TAAR1 (0.56) | TSHRCFTRALDH1A1TAAR1F2RL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105431427-B | Novel PDE 4 inhibitor | 明治制果药业株式会社 | 2017-12-08 | — | — | CN | disclosed |
| EP-2961373-A2 | ORAL CARE COMPOSITIONS | JOHNSON & JOHNSON CONSUMER INC. (US) | 2016-01-06 | — | — | EP | disclosed |
| WO-2014133746-A2 | ORAL CARE COMPOSITIONS | MCNEIL-PPC, INC. (US) | 2014-09-04 | — | — | WO | disclosed |
| US-4764521-A | Leukotriene antagonists and a method of use there as | ELI LILLY AND COMPANY (US) | 1988-08-16 | — | — | US | disclosed |
| EP-0132367-B1 | LEUKOTRIENE ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1988-06-08 | — | — | EP | disclosed |
| EP-0132367-A2 | Leukotriene antagonists | ELI LILLY AND COMPANY (US) | 1985-01-30 | — | — | EP | disclosed |