Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 2/20 | 0.51 |
| ▸ | MC5R | P33032 | 2/20 | 0.51 |
| ▸ | MC3R | P41968 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CASP2 | P42575 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | F13A1 | P00488 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | CA6 | P23280 | 2/20 | 0.38 |
| ▸ | CA5A | P35218 | 2/20 | 0.38 |
| ▸ | THPO | P40225 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16151783 | 0.82 | MC4R (0.58) | MC4RMC5RMC3RCHRM2CASP2 | |
| Hydrochloric Acid SCHEMBL29778318 | 0.80 | MC4R (0.56) | MC4RMC5RMC3RCHRM2CASP2 | |
| SCHEMBL10483900 | 0.80 | LOXL2 (0.56) | MC4RMC5RMC3RCHRM2ALOX15 | |
| SCHEMBL16435203 | 0.78 | MC4R (0.55) | MC4RMC5RMC3RCASP2CA12 | |
| SCHEMBL16151766 | 0.78 | MC4R (0.55) | MC4RMC5RMC3RCASP2CA12 | |
| SCHEMBL10483951 | 0.78 | MC4R (0.51) | MC4RMC5RMC3RCHRM2CASP2 | |
| SCHEMBL7995630 | 0.77 | FNTA (0.36) | MC4RMC5RCHRM2CYP1A2MEN1 | |
| Hydrochloric Acid SCHEMBL29778304 | 0.76 | UBE2N (0.54) | MC4RMC5RMC3RCASP2CA12 | |
| SCHEMBL2761649 | 0.74 | CA12 (0.56) | MC4RMC5RMC3RCHRM2CASP2 | |
| SCHEMBL16152227 | 0.74 | CA12 (0.50) | MC4RMC5RMC3RCHRM2CASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4774247-A | Nitromethylene derivative insecticides | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1988-09-27 | — | — | US | disclosed |
| US-4678795-A | 1-pyridylmethyl-2-nitromethylene-1,3-diazacycloalkane insecticides | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1987-07-07 | — | — | US | disclosed |
| EP-0163855-A1 | Nitromethylene derivatives, intermediates, and process for their preparation as insecticides | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1985-12-11 | — | — | EP | disclosed |