Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10642938 | 0.89 | KMT2A (0.41) | GAAALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL10637719 | 0.89 | FPR1 (0.42) | GAAALDH1A1KDM4ELMNAHSD17B10 | |
| SCHEMBL10642253 | 0.87 | HTT (0.44) | GAAALDH1A1HPGDLMNAHTT | |
| SCHEMBL10642654 | 0.87 | SMN1; SMN2 (0.47) | GAAALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL10640610 | 0.86 | HTR2C (0.39) | GAAALDH1A1KDM4ECYP2C9CYP2C19 | |
| SCHEMBL10641116 | 0.86 | TP53 (0.45) | ALDH1A1CYP2C9CYP2C19CYP3A4CYP2D6 | |
| SCHEMBL10641240 | 0.85 | FPR1 (0.40) | GAAALDH1A1KDM4EHTTPDE4B | |
| SCHEMBL10642036 | 0.84 | KMT2A (0.41) | GAAALDH1A1KDM4ELMNAHSD17B10 | |
| SCHEMBL10643991 | 0.84 | GPBAR1 (0.43) | ALDH1A1KDM4ELMNAHTTTSHR | |
| SCHEMBL10639201 | 0.82 | SLC6A4 (0.44) | GAAALDH1A1KDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0164853-B1 | (SUBSTITUTED-PHENYL)-5-OXO-2-PYRROLIDINEPROPANOIC ACIDS, A PROCESS FOR PRODUCING THE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE COMPOUNDS | WARNER-LAMBERT COMPANY (US) | 1988-07-06 | — | — | EP | disclosed |
| US-4584313-A | TREATING SENILITY | WARNER-LAMBERT COMPANY (US) | 1986-04-22 | — | — | US | disclosed |