FPR1 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL764675	0.53	17/20
SCHEMBL470778	0.53	10/20
SCHEMBL892757	0.47	8/20
SCHEMBL85529	0.52	7/20
SCHEMBL388221	0.47	7/20
SCHEMBL953684	0.82	6/20
SCHEMBL953685	0.82	6/20
SCHEMBL954590	0.72	6/20
SCHEMBL954591	0.72	6/20
SCHEMBL778839	0.55	5/20
SCHEMBL681885	0.45	5/20
SCHEMBL397897	1.00	4/20
SCHEMBL397898	1.00	4/20
N-Formylmethionyl-Leucylphenylalanine (SCHEMBL39528)	0.61	4/20
N-Formylmethionyl-Leucylphenylalanine (SCHEMBL39529)	0.61	4/20
SCHEMBL791975	0.59	4/20
Benzaldehyde (SCHEMBL873319)	0.59	4/20
SCHEMBL952913	0.58	4/20
SCHEMBL952915	0.58	4/20
SCHEMBL76526	0.52	4/20

Clinical trials — most relevant to FPR1 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Intraoperative Infusion of Precedex to Reduce Length of Stay After Lumbar Spine Fusion	PHASE4	COMPLETED
Efficacy of DEXamethasone in Patients With Acute Hypoxemic REspiratory Failure Caused by INfEctions	PHASE4	RECRUITING
The Role of High Dose Co-trimoxazole in Severe Covid-19 Patients	PHASE2/PHASE3	COMPLETED
Triamcinolone Versus Methylprednisolone in Transversus Abdominis Plane Block	PHASE2/PHASE3	COMPLETED
Ramatroban/Montelukast Versus Montelukast/Placebo on the Early Allergic Reaction in Asthma Sensitive to House Dust Mite	PHASE2/PHASE3	WITHDRAWN
Montelukast for Early Life Wheezing	PHASE2/PHASE3	COMPLETED
Electrophilic Fatty Acid Derivatives in Asthma	PHASE1	COMPLETED
Pro-Resolving Mediators in Acute Inflammation in Humans	EARLY_PHASE1	COMPLETED
The Severe Asthma Research Program III-Boston Clinical Site	nan	COMPLETED
FGL2/Fibroleukin and Hepatitis C Virus Recurrence Post Liver Transplantation	nan	UNKNOWN
Gluten-related Disorders in Familial Mediterranean Fever Patients	nan	COMPLETED
NETs: Protection or Harm in Neonatal Inflammation or Infection	nan	RECRUITING
Evaluation of Serum Follistatin-Like Protein 1 Levels in Behcet's Disease and Its Association With Disease Activity	nan	COMPLETED
In Vitro Studies on Pharmacological Regulation and Genetic Risk Factors of Peripheral Human Nociceptors	nan	COMPLETED
Study of the Functional Status Neutrophils in Rheumatoid Arthritis Patients to Identify New Biomarkers of Response to Anti-TNFalpha Therapy	nan	UNKNOWN
Aspirin and Neutrophils in Preeclampsia	nan	COMPLETED
Suppression of Postprandial Monocyte Activation by Blueberries or Docosahexaenoic Acid in Humans	nan	COMPLETED
The Role of Neutrophil CD64 and Soluble Triggering Receptor Expressed on Myeloid Cells 1 in Neonatal Sepsis	nan	UNKNOWN
Effects of n3 LC PUFAs on Inflammatory, Immune and Senescence Features in Polyvascular Older Subjects (OMSAGE)	nan	NOT_YET_RECRUITING
Assessment of Vitamin D Supplementation and Immune Function	nan	COMPLETED
Role of Nox2 in CNI-induced Renal Fibrosis	nan	COMPLETED
Lipid Mediators in Multiple Sclerosis	nan	COMPLETED
In Vitro Demonstration of Direct Platelet-Related Effects of PCSK9 Enzyme	nan	NOT_YET_RECRUITING
Potential Role of Inflammasome NLRP3 And IL-1B Gene Expression in COVID-19 Patients: Impact of Ferretin and D -Dimer.	nan	UNKNOWN
Assessment of CXCL5 Level in SLE Patients and Its Correlation with Disease Activity	nan	NOT_YET_RECRUITING
Pathogenic Mechanisms in C Diff Infection and Colitis	nan	COMPLETED
Investigation of Lipoxin A4, Annexin A1 and Interleukin-1 Beta Levels in Individuals With Periodontitis.	nan	COMPLETED
The Effects of Lipinova on Inflammatory and Proresolving Lipid Mediator Profiles After Orthopedic Surgery	nan	UNKNOWN
The Role of Stromal Cell-Derived Factor-1 (SDF-1)/CXC Chemokine Receptor 4 (CXCR4) in Metastasis of Laryngeal and Hypopharyngeal Squamous Cell Carcinoma	nan	UNKNOWN
Neutrophil FFA2/GPR43 Receptor Expression in Patients With the Diagnosis of Sepsis	nan	WITHDRAWN

Related proteins — ESM-2 sequence neighbours (a FPR1 binder may also engage these)

Protein	Name	Similarity
P79235	—	1.000	P79235 →
P79190	—	1.000	P79190 →
P79241	—	1.000	P79241 →
P79176	—	1.000	P79176 →
P79242	—	1.000	P79242 →
P79236	—	1.000	P79236 →
Q05394	—	0.999	Q05394 →
P79189	—	0.999	P79189 →
P79177	—	0.996	P79177 →
FPR2	N-formyl peptide receptor 2	0.996	landscape →
P79243	—	0.996	P79243 →
P33766	—	0.994	P33766 →
P79237	—	0.994	P79237 →
O88536	—	0.994	O88536 →
Q3SXG2	—	0.993	Q3SXG2 →
FPR3	N-formyl peptide receptor 3	0.992	landscape →
O88537	—	0.991	O88537 →
P79178	—	0.991	P79178 →
P0C7U4	—	0.990	P0C7U4 →
P79240	—	0.990	P79240 →
Q49SP8	—	0.990	Q49SP8 →
P79191	—	0.990	P79191 →
P30993	—	0.989	P30993 →
A4FUQ5	—	0.989	A4FUQ5 →
O08790	—	0.989	O08790 →
Q71MR7	—	0.988	Q71MR7 →
Q49SQ2	—	0.988	Q49SQ2 →
Q49SQ3	—	0.987	Q49SQ3 →
C5AR1	C5a anaphylatoxin chemotactic receptor 1	0.987	landscape →
Q49SQ1	—	0.986	Q49SQ1 →