SCHEMBL10636765

SCHEMBL10636765

CCOCCOc1ccc(C[C@@H](C)NC(=O)CCOc2ccccc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ACACB O00763 18/20 0.64
PSMB5 P28074 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10636768 1.00 ACACB (0.64) ACACBPSMB5
SCHEMBL9782119 0.85 ACACB (0.72) ACACB
SCHEMBL9787803 0.81 ACACB (0.63) ACACB
SCHEMBL256292 0.80 ACACB (0.82) ACACB
SCHEMBL9684259 0.79 ACACB (0.54) ACACB
SCHEMBL9787808 0.78 ACACB (0.57) ACACB
SCHEMBL26502873 0.78 NPC1 (0.55) ACACB
SCHEMBL11998669 0.78 ACACB (1.00) ACACB
SCHEMBL12001106 0.76 ACACB (0.83) ACACB
SCHEMBL8258564 0.75 CYP1A2 (0.61) PSMB5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0140243-B1 PHENOXYPROPANOL AMINES F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1988-11-09 EP claimed
EP-0140243-A2 Phenoxypropanol amines F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1985-05-08 EP claimed