Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25729410 | 1.00 | TSHR (0.42) | TSHRMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL17970303 | 0.98 | TSHR (0.40) | TSHRMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL25729159 | 0.91 | TSHR (0.46) | TSHRMEN1KMT2A | |
| SCHEMBL25729019 | 0.88 | TSHR (0.43) | TSHRMEN1KMT2A | |
| SCHEMBL24636720 | 0.87 | ALDH1A1 (0.44) | TSHRMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL11158159 | 0.87 | ALDH1A1 (0.33) | TSHRALDH1A1 | |
| SCHEMBL25728861 | 0.86 | TSHR (0.50) | TSHRMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL17935756 | 0.84 | ALDH1A1 (0.41) | TSHRMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL21842109 | 0.83 | ALDH1A1 (0.37) | TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL25728874 | 0.83 | TSHR (0.35) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4721710-A | Derivatives of piperidinedione for protecting the myocardium presenting an anti-arrythmic activity, and pharmaceutical compositions | SANOFI | 1988-01-26 | — | — | US | disclosed |