Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | KMO | O15229 | 1/20 | 0.31 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10642807 | 0.77 | ALDH1A1 (0.59) | ALDH1A1TDP1APPMAPTHTT | |
| SCHEMBL4947244 | 0.71 | ALDH1A1 (0.36) | ALDH1A1APPTSHRMAPK1KMO | |
| SCHEMBL22356490 | 0.69 | ALDH1A1 (0.91) | ALDH1A1TDP1MAPTHTTTSHR | |
| SCHEMBL1042543 | 0.69 | ALDH1A1 (0.47) | ALDH1A1APPNISCHMAPTHTT | |
| SCHEMBL6487453 | 0.68 | ALDH1A1 (0.34) | ALDH1A1APPMAPTTSHRKMT2A | |
| SCHEMBL654423 | 0.68 | MAPK1 (0.42) | ALDH1A1MEN1KMT2AMAPK1ADORA2A | |
| SCHEMBL1392897 | 0.68 | NISCH (0.45) | APPNISCHADORA2AADORA1KMO | |
| SCHEMBL17272907 | 0.68 | ALDH1A1 (0.41) | ALDH1A1APPNISCHMAPTHTT | |
| SCHEMBL10639157 | 0.66 | ALDH1A1 (0.57) | ALDH1A1TDP1MAPTHTTTSHR | |
| SCHEMBL14107188 | 0.66 | ALDH1A1 (0.45) | ALDH1A1CA12CA1CA2NISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0258391-A1 | USE OF HETEROCYCLIC NITROGEN-CONTAINING COMPOUNDS FOR REDUCING MOISTURE LOSS FROM PLANTS AND INCREASING CROP YIELD | RHONE POULENC NEDERLAND B.V. (NL) | 1988-03-09 | — | — | EP | disclosed |
| WO-1987004321-A2 | USE OF HETEROCYCLIC NITROGEN-CONTAINING COMPOUNDS FOR REDUCING MOISTURE LOSS FROM PLANTS AND INCREASING CROP YIELD | RHONE-POULENC NEDERLANDS B.V. (NL) | 1987-07-30 | — | — | WO | disclosed |