Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid Ethyl Ester SCHEMBL10578284 | 0.92 | HCAR2 (0.58) | HCAR2ALDH1A1NPSR1CYP2D6SMN1; SMN2 | |
| Acrylic Acid Methyl Ester SCHEMBL10947152 | 0.89 | HCAR2 (0.50) | HCAR2ALDH1A1NPSR1GLO1CYP2D6 | |
| Acrylic Acid Ethyl Ester SCHEMBL7588959 | 0.82 | HCAR2 (0.46) | HCAR2ALDH1A1NPSR1CYP2D6SMN1; SMN2 | |
| Ethyl Fumarate SCHEMBL11309874 | 0.80 | HCAR2 (0.83) | HCAR2ALDH1A1NPSR1LMNATSHR | |
| Ethyl Fumarate SCHEMBL9467940 | 0.80 | HCAR2 (0.83) | HCAR2ALDH1A1NPSR1LMNATSHR | |
| Ethyl Fumarate SCHEMBL2776691 | 0.80 | HCAR2 (0.83) | HCAR2ALDH1A1NPSR1LMNATSHR | |
| Acrylic Acid SCHEMBL29212705 | 0.79 | LMNA (0.50) | HCAR2ALDH1A1NPSR1GLO1CYP2D6 | |
| Acrylic Acid SCHEMBL11216503 | 0.79 | HCAR2 (0.52) | HCAR2ALDH1A1NPSR1GLO1CYP2D6 | |
| SCHEMBL10830326 | 0.78 | HCAR2 (0.51) | HCAR2ALDH1A1NPSR1SMN1; SMN2LMNA | |
| SCHEMBL754655 | 0.76 | MAPT (0.41) | HCAR2ALDH1A1SMN1; SMN2TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4783500-A | ORGANO-SILICON,-TIN, OR -GERMANIUM INITIATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-11-08 | — | — | US | disclosed |
| US-4711942-A | FROM ACRYLIC OR MALEIMIDE MONOMER AND ORGANOSILICON,-TIN, OR -GERMANIUM INITIATOR | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-12-08 | — | — | US | disclosed |
| US-4681918-A | ACRYLIC-TYPE OR MALEIMIDE MONOMERS; ORGANOSILICON, TIN OR GERMANIUM INITIATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-07-21 | — | — | US | disclosed |
| US-4508880-A | ACRYLIC OR MALEIMIDE MONOMERS WITH ORGANOSILICON, (-TIN, OR-GERMANIUM) INITIATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-04-02 | — | — | US | disclosed |