Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10641181 | 1.00 | KDM4E (0.48) | KDM4ELMNAALDH1A1HPGDAKR1C3 | |
| SCHEMBL10635337 | 0.91 | KDM4E (0.43) | KDM4ELMNAALDH1A1HPGDPPARA | |
| SCHEMBL10635333 | 0.91 | KDM4E (0.43) | KDM4ELMNAALDH1A1HPGDPPARA | |
| SCHEMBL10638443 | 0.88 | KDM4E (0.47) | KDM4EALDH1A1HPGDPPARAHDAC1 | |
| SCHEMBL10638439 | 0.88 | KDM4E (0.47) | KDM4EALDH1A1HPGDPPARAHDAC1 | |
| SCHEMBL10635838 | 0.87 | PPARA (0.42) | KDM4EALDH1A1PPARAPKMBACE1 | |
| SCHEMBL10635845 | 0.87 | PPARA (0.42) | KDM4EALDH1A1PPARAPKMBACE1 | |
| SCHEMBL10635807 | 0.85 | PPARA (0.41) | KDM4ELMNAALDH1A1HPGDPPARA | |
| SCHEMBL10635836 | 0.85 | PPARA (0.41) | KDM4ELMNAALDH1A1HPGDPPARA | |
| SCHEMBL10638488 | 0.84 | PPARA (0.60) | KDM4EALDH1A1HPGDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0134337-B1 | SUBSTITUTED 2,2-DIMETHYL-5-PHENOXYPENTANOIC ACID BENZAMIDES AND THEIR PRODUCTION | WARNER-LAMBERT COMPANY (US) | 1988-01-07 | — | — | EP | claimed |