Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 5/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 8/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.43 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 6/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10638443 | 1.00 | KDM4E (0.47) | KDM4EPPARATRPV1ACHESMN1; SMN2 | |
| SCHEMBL10635845 | 0.91 | PPARA (0.42) | KDM4EPPARATRPV1SMN1; SMN2TTR | |
| SCHEMBL10635838 | 0.91 | PPARA (0.42) | KDM4EPPARATRPV1SMN1; SMN2TTR | |
| SCHEMBL10640004 | 0.89 | FDPS (0.53) | KDM4EPPARATRPV1ACHETTR | |
| SCHEMBL10640001 | 0.89 | FDPS (0.53) | KDM4EPPARATRPV1ACHETTR | |
| SCHEMBL10641181 | 0.88 | KDM4E (0.48) | KDM4EPPARAHDAC1ALDH1A1HPGD | |
| SCHEMBL10641174 | 0.88 | KDM4E (0.48) | KDM4EPPARAHDAC1ALDH1A1HPGD | |
| SCHEMBL10638488 | 0.88 | PPARA (0.60) | KDM4EPPARASMN1; SMN2TTRCYP1A2 | |
| SCHEMBL10638480 | 0.88 | PPARA (0.60) | KDM4EPPARASMN1; SMN2TTRCYP1A2 | |
| SCHEMBL10635646 | 0.84 | PPARA (0.40) | KDM4EPPARAACHESMN1; SMN2TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0134337-B1 | SUBSTITUTED 2,2-DIMETHYL-5-PHENOXYPENTANOIC ACID BENZAMIDES AND THEIR PRODUCTION | WARNER-LAMBERT COMPANY (US) | 1988-01-07 | — | — | EP | claimed |