Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10641820 | 1.00 | CA1 (0.39) | CA1CA2ACHEUSP2TSHR | |
| SCHEMBL4327520 | 1.00 | CA1 (0.39) | CA1CA2ACHEUSP2TSHR | |
| SCHEMBL20640842 | 0.91 | DPP4 (0.35) | CA1CA2ACHEUSP2TSHR | |
| SCHEMBL3815211 | 0.90 | — | — | |
| SCHEMBL14779612 | 0.90 | USP2 (0.33) | CA1CA2USP2TSHR | |
| SCHEMBL2580348 | 0.87 | ACHE (0.34) | CA1CA2ACHE | |
| SCHEMBL10641393 | 0.87 | CA1 (0.34) | CA1CA2ACHETSHR | |
| SCHEMBL2580350 | 0.87 | ACHE (0.34) | CA1CA2ACHE | |
| SCHEMBL10641386 | 0.87 | CA1 (0.34) | CA1CA2ACHETSHR | |
| SCHEMBL2580352 | 0.87 | ACHE (0.34) | CA1CA2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4720505-A | Leukotriene antagonists | MERCK FROSST CANADA, INC. (CA) | 1988-01-19 | — | — | US | disclosed |