Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MDM4 | O15151 | 1/20 | 0.41 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28380686 | 0.80 | SMN1; SMN2 (0.61) | ARGAASMN1; SMN2L3MBTL1NR1I2 | |
| SCHEMBL27176695 | 0.76 | SMN1; SMN2 (0.63) | ARGAASMN1; SMN2L3MBTL1NR1I2 | |
| SCHEMBL27176681 | 0.74 | SMN1; SMN2 (0.64) | ARGAASMN1; SMN2L3MBTL1NR1I2 | |
| SCHEMBL15318838 | 0.74 | CA1 (0.54) | ARGAASMN1; SMN2PKMCA1 | |
| SCHEMBL29592713 | 0.74 | CA1 (0.54) | ARGAASMN1; SMN2PKMCA1 | |
| SCHEMBL641243 | 0.72 | SMN1; SMN2 (0.64) | ARGAASMN1; SMN2L3MBTL1NR1I2 | |
| SCHEMBL31235173 | 0.71 | AR (0.67) | ARGAASMN1; SMN2L3MBTL1PKM | |
| SCHEMBL410747 | 0.71 | AR (0.67) | ARGAASMN1; SMN2L3MBTL1PKM | |
| SCHEMBL13689981 | 0.71 | SMN1; SMN2 (0.60) | ARGAASMN1; SMN2L3MBTL1NR1I2 | |
| SCHEMBL6343982 | 0.71 | SMN1; SMN2 (0.60) | ARGAASMN1; SMN2L3MBTL1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0136729-B1 | PESTICIDAL BENZOYLUREA DERIVATIVES | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1988-02-03 | — | — | EP | disclosed |