Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | MMP1 | P03956 | 1/20 | 0.55 |
| ▸ | MMP2 | P08253 | 1/20 | 0.55 |
| ▸ | MMP9 | P14780 | 1/20 | 0.55 |
| ▸ | MMP8 | P22894 | 1/20 | 0.55 |
| ▸ | MMP13 | P45452 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | AR | P10275 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.49 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27176695 | 0.87 | SMN1; SMN2 (0.63) | SMN1; SMN2GAAL3MBTL1CA1CA2 | |
| SCHEMBL27176681 | 0.85 | SMN1; SMN2 (0.64) | SMN1; SMN2GAAL3MBTL1CA1CA2 | |
| SCHEMBL641243 | 0.82 | SMN1; SMN2 (0.64) | SMN1; SMN2GAAL3MBTL1CA1CA2 | |
| SCHEMBL410747 | 0.82 | AR (0.67) | SMN1; SMN2GAAL3MBTL1CA1CA2 | |
| SCHEMBL31235173 | 0.82 | AR (0.67) | SMN1; SMN2GAAL3MBTL1CA1CA2 | |
| SCHEMBL13602263 | 0.80 | L3MBTL1 (0.63) | SMN1; SMN2GAAL3MBTL1CA1CA2 | |
| SCHEMBL10642502 | 0.80 | AR (0.50) | SMN1; SMN2GAAL3MBTL1CA1CA2 | |
| SCHEMBL6534664 | 0.79 | CA1 (0.58) | SMN1; SMN2GAAL3MBTL1CA1CA2 | |
| SCHEMBL13689981 | 0.79 | SMN1; SMN2 (0.60) | SMN1; SMN2GAAL3MBTL1CA1CA2 | |
| SCHEMBL5227061 | 0.78 | GAA (0.59) | SMN1; SMN2GAAL3MBTL1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114404602-A | Solid dispersant of benzamide compound and application thereof | 中国医学科学院医药生物技术研究所 | 2022-04-29 | — | — | CN | claimed |
| CN-114404602-A | Solid dispersant of benzamide compound and application thereof | 中国医学科学院医药生物技术研究所 | 2022-04-29 | — | — | CN | disclosed |
| CN-110840836-B | Benzamide compound IMB16-4 nano suspension and preparation method thereof | 中国医学科学院医药生物技术研究所 | 2021-11-26 | — | — | CN | disclosed |
| CN-110840836-A | Benzamide compound IMB16-4 nano suspension and preparation method thereof | 中国医学科学院医药生物技术研究所 | 2020-02-28 | — | — | CN | disclosed |