⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11059682 | 0.85 | — | — | |
| SCHEMBL9148558 | 0.80 | — | — | |
| SCHEMBL11691557 | 0.79 | — | — | |
| SCHEMBL4160084 | 0.68 | — | — | |
| SCHEMBL11748676 | 0.64 | PGR (0.30) | — | |
| SCHEMBL11752327 | 0.61 | — | — | |
| SCHEMBL383233 | 0.61 | — | — | |
| SCHEMBL9410417 | 0.60 | GAA (0.33) | — | |
| SCHEMBL3200423 | 0.56 | — | — | |
| SCHEMBL2117309 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0145226-B1 | SUBSTITUTED 1-AMINO-4-NITRO-ACRIDINONES, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME AND PROCESSES FOR THEIR PRODUCTION | WARNER-LAMBERT COMPANY (US) | 1988-10-05 | — | — | EP | disclosed |
| US-4626540-A | Substituted 1-amino-4-nitro-acridinones and methods of treating bacterial infections and leukemia with them | WARNER-LAMBERT COMPANY (US) | 1986-12-02 | — | — | US | disclosed |
| US-4626540-A | Substituted 1-amino-4-nitro-acridinones and methods of treating bacterial infections and leukemia with them | WARNER-LAMBERT COMPANY (US) | 1986-12-02 | — | — | US | disclosed |
| EP-0145226-A2 | Substituted 1-amino-4-nitro-acridinones, pharmaceutical compositions comprising the same and processes for their production | WARNER-LAMBERT COMPANY (US) | 1985-06-19 | — | — | EP | disclosed |
| EP-0145226-A2 | Substituted 1-amino-4-nitro-acridinones, pharmaceutical compositions comprising the same and processes for their production | WARNER-LAMBERT COMPANY (US) | 1985-06-19 | — | — | EP | disclosed |
| US-3932414-A | PIGMENTS FOR POLYMERS, PAPER, PAINTS, INKS, LACQUERS | SANDOZ LTD., (SANDOZ AG) (CH) | 1976-01-13 | — | — | US | disclosed |