Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4556064 | 0.81 | HRH3 (0.44) | HRH3MAPTALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL24114952 | 0.81 | HRH3 (0.44) | HRH3MAPTALDH1A1L3MBTL1MAPK1 | |
| Water SCHEMBL28467825 | 0.79 | HRH3 (0.42) | HRH3MAPTALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL24604493 | 0.79 | OPRM1 (0.39) | HRH3MAPTALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL4274466 | 0.79 | OPRM1 (0.39) | HRH3MAPTALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL28224805 | 0.79 | OPRM1 (0.39) | HRH3MAPTALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL28237829 | 0.78 | HRH3 (0.41) | HRH3MAPTALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL3869954 | 0.78 | HRH3 (0.41) | HRH3MAPTALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL24998924 | 0.77 | HRH3 (0.38) | HRH3MAPTALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL15740500 | 0.77 | HRH3 (0.38) | HRH3MAPTALDH1A1L3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0131374-B1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF PENEM DERIVATIVES | PFIZER INC. (US) | 1988-11-23 | — | — | EP | disclosed |