Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 6/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10648421 | 0.99 | CYP11B1 (0.46) | CYP11B1CYP11B2KMT2AMEN1KDM4E | |
| SCHEMBL10648854 | 0.81 | CYP11B1 (0.47) | CYP11B1CYP11B2KMT2AMEN1KDM4E | |
| SCHEMBL10648690 | 0.80 | CYP11B1 (0.46) | CYP11B1CYP11B2KMT2AMEN1KDM4E | |
| SCHEMBL10650460 | 0.80 | CYP11B1 (0.46) | CYP11B1CYP11B2KDM4ECYP2D6POLB | |
| Hydrochloric Acid SCHEMBL10646340 | 0.80 | CYP11B1 (0.46) | CYP11B1CYP11B2KMT2AMEN1KDM4E | |
| Hydrochloric Acid SCHEMBL10648181 | 0.80 | CYP11B1 (0.46) | CYP11B1CYP11B2KDM4ECYP2D6POLB | |
| Hydrochloric Acid SCHEMBL10651008 | 0.80 | CYP11B1 (0.46) | CYP11B1CYP11B2KMT2AMEN1KDM4E | |
| SCHEMBL10650408 | 0.79 | CYP11B1 (0.45) | CYP11B1CYP11B2KMT2AMEN1KDM4E | |
| SCHEMBL10646977 | 0.79 | CYP11B1 (0.45) | CYP11B1CYP11B2KMT2AMEN1KDM4E | |
| Hydrochloric Acid SCHEMBL10648154 | 0.78 | CYP11B1 (0.44) | CYP11B1CYP11B2KMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0128502-B1 | SUBSTITUTED 6-(THIEN-2-YL)-3(2H)-PYRIDAZINONES AND PROCESSES FOR THEIR PREPARATION | A. Nattermann & Cie. GmbH (DE) | 1988-08-31 | — | — | EP | disclosed |