Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ALPL | P05186 | 1/20 | 0.50 |
| ▸ | ALPG | P10696 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9625464 | 1.00 | ALDH1A1 (0.56) | ALDH1A1GRIN2BMEN1KMT2AALPL | |
| Hydrochloric Acid SCHEMBL9624778 | 0.99 | ALDH1A1 (0.55) | ALDH1A1GRIN2BMEN1KMT2AALPL | |
| Hydrochloric Acid SCHEMBL9624458 | 0.99 | ALDH1A1 (0.55) | ALDH1A1GRIN2BMEN1KMT2AALPL | |
| SCHEMBL11819902 | 0.86 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2ATSHRLTA4H | |
| SCHEMBL10359739 | 0.85 | POLB (0.57) | ALDH1A1GRIN2BMEN1KMT2AMAPT | |
| SCHEMBL9513472 | 0.85 | ALDH1A1 (0.61) | ALDH1A1GRIN2BMEN1KMT2AHTT | |
| SCHEMBL11817960 | 0.84 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2ATSHRLTA4H | |
| SCHEMBL9444257 | 0.83 | KCNH2 (0.60) | ALDH1A1GRIN2BMEN1KMT2ATSHR | |
| SCHEMBL9513736 | 0.80 | POLB (0.49) | ALDH1A1GRIN2BMEN1KMT2ATSHR | |
| SCHEMBL10644710 | 0.79 | NPSR1 (0.64) | ALDH1A1MEN1KMT2AHPGDHDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0164865-B1 | N-(AMINOALKYLPHENYL)SULFONAMIDES THEIR PREPARATION AND THERAPEUTIC USE | THE UPJOHN COMPANY (US) | 1988-12-21 | — | — | EP | disclosed |