Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | TLR4 | O00206 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 4/20 | 0.37 |
| ▸ | CA2 | P00918 | 4/20 | 0.37 |
| ▸ | CA9 | Q16790 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10863304 | 0.98 | MEN1 (0.46) | PRSS1PRSS2PRSS3MEN1KMT2A | |
| SCHEMBL10863259 | 0.93 | — | — | |
| Hydrochloric Acid SCHEMBL27509463 | 0.80 | MEN1 (0.35) | MEN1KMT2AESR1TLR4 | |
| Hydrochloric Acid SCHEMBL11080405 | 0.80 | — | — | |
| SCHEMBL10767591 | 0.78 | ESR1 (0.41) | MEN1KMT2AESR1MAPTCA1 | |
| SCHEMBL18474063 | 0.76 | — | — | |
| SCHEMBL10142035 | 0.76 | CES2 (0.43) | MEN1KMT2AESR1MAPTTHRB | |
| Propanol SCHEMBL27533076 | 0.76 | TSHR (0.31) | MEN1KMT2A | |
| SCHEMBL17697701 | 0.73 | ESR1 (0.38) | MEN1KMT2AESR1MAPTCA1 | |
| SCHEMBL17697759 | 0.71 | MEN1 (0.38) | MEN1KMT2AESR1MAPTCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0173322-B1 | 1-(2-OXYAMINOSULFONYLPHENYL-SULFONYL)-3-HETEROARYL UREAS | BAYER AG (DE) | 1988-12-28 | — | — | EP | disclosed |
| EP-0173317-A1 | Unsymmetrical sulfonyl guanidines | BAYER AG (DE) | 1986-03-05 | — | — | EP | disclosed |
| EP-0173315-A1 | Oxyguanidine derivatives | BAYER AG (DE) | 1986-03-05 | — | — | EP | disclosed |