Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RHEB | Q15382 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | GUSB | P08236 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10530492 | 0.88 | TOP1 (0.47) | ALDH1A1HPGDHSD17B10RHEBGUSB | |
| SCHEMBL10532272 | 0.86 | RHEB (0.46) | ALDH1A1KDM4EHPGDHSD17B10CYP1A2 | |
| SCHEMBL10532273 | 0.86 | SLC2A1 (0.46) | ALDH1A1KDM4EHPGDHSD17B10PDE3B | |
| SCHEMBL10531303 | 0.84 | RHEB (0.43) | ALDH1A1KDM4EHPGDHSD17B10CYP1A2 | |
| SCHEMBL10534126 | 0.84 | RHEB (0.44) | ALDH1A1KDM4EHPGDHSD17B10CYP1A2 | |
| SCHEMBL10530451 | 0.81 | CBFB (0.52) | ALDH1A1KDM4EHPGDHSD17B10NPC1 | |
| SCHEMBL10697017 | 0.78 | ALDH1A1 (0.49) | ALDH1A1KDM4EHPGDHSD17B10CYP1A2 | |
| SCHEMBL10530509 | 0.76 | ALDH1A1 (0.45) | ALDH1A1KDM4EHPGDHSD17B10CYP1A2 | |
| SCHEMBL10646624 | 0.76 | PDE4A (0.56) | ALDH1A1KDM4EHPGDHSD17B10CYP1A2 | |
| Water SCHEMBL10532213 | 0.76 | PDE4A (0.55) | ALDH1A1KDM4EHPGDHSD17B10CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0263352-A1 | Imidazo-benzoxazinones, their preparation and medicaments containing these compounds | Dr. Karl Thomae GmbH (DE) | 1988-04-13 | — | — | EP | disclosed |