SCHEMBL10646751

SCHEMBL10646751

O=C1N[C@H]2CCCC[C@@H]12

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12380067 1.00
SCHEMBL14306026 1.00
SCHEMBL10646748 1.00
SCHEMBL18994415 1.00
SCHEMBL774979 1.00
SCHEMBL12380168 1.00
SCHEMBL12325998 0.97 LMNA (0.46)
SCHEMBL12380113 0.97 LMNA (0.46)
SCHEMBL18994414 0.97 LMNA (0.46)
SCHEMBL14478529 0.97 LMNA (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170247510-A1 POLY-BETA-PEPTIDES FROM FUNCTIONALIZED BETA-LACTAM MONOMERS AND ANTIBACTERIAL COMPOSITIONS CONTAINING SAME NATIONAL SCIENCE FOUNDATION 2017-08-31 US disclosed
US-9683081-B2 Poly-beta-peptides from functionalized beta-lactam monomers and antibacterial compositions containing same WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2017-06-20 US disclosed
US-9120892-B2 Poly-β-peptides from functionalized β-lactam monomers and antibacterial compositions containing same WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2015-09-01 US disclosed
US-20150231171-A1 NYLON-3 CO-POLYMERS AND SYNTHETIC LUNG SURFACTANT COMPOSITIONS CONTAINING SAME WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2015-08-20 US disclosed
US-9044392-B2 Nylon-3 co-polymers and synthetic lung surfactant compositions containing same WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2015-06-02 US disclosed
US-8519095-B2 Poly-beta-peptides from functionalized beta-lactam monomers and antibacterial compositions containing same WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2013-08-27 US disclosed
US-20130004453-A1 NYLON-3 CO-POLYMERS AND SYNTHETIC LUNG SURFACTANT COMPOSITIONS CONTAINING SAME NATIONAL SCIENCE FOUNDATION 2013-01-03 US disclosed
WO-2012160030-A1 PYRIDIN-2 (1H) -ONE DERIVATIVES USEFUL AS MEDICAMENTS FOR THE TREATMENT OF MYELOPROLIFERATIVE DISORDERS, TRANSPLANT REJECTION, IMMUNE-MEDIATED AND INFLAMMATORY DISEASES ALMIRALL, S.A. (ES) 2012-11-29 WO disclosed
EP-1461315-B1 CATALYTIC CARBONYLATION OF THREE AND FOUR MEMBERED HETEROCYCLES CORNELL RES FOUNDATION INC (US) 2009-07-29 EP disclosed
US-20070087404-A1 Poly-beta-peptides from functionalized beta-lactam monomers and antibacterial compositions containing same WISCONSIN ALUMNI RESEARCH FOUNDATION 2007-04-19 US disclosed
WO-2007025141-A2 POLY-BETA-PEPTIDES FROM FUNCTIONALIZED BETA-LACTAM MONOMERS AND ANTIBACTERIAL COMPOSITIONS CONTAINING SAME WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2007-03-01 WO disclosed
EP-0282492-A1 ANTIMICROBIAL N-ACYL-2-AZETIDINONES THE UPJOHN COMPANY (US) 1988-09-21 EP disclosed
EP-0232017-A1 Antimicrobial N-acyl-2-azetidinones THE UPJOHN COMPANY (US) 1987-08-12 EP disclosed
WO-1987004429-A1 ANTIMICROBIAL N-ACYL-2-AZETIDINONES THE UPJOHN COMPANY (US) 1987-07-30 WO disclosed