Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 7/20 | 0.76 |
| ▸ | HDAC7 | Q8WUI4 | 7/20 | 0.76 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.76 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.76 |
| ▸ | MLYCD | O95822 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 3/20 | 0.51 |
| ▸ | CA2 | P00918 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.47 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5785443 | 0.83 | HDAC1 (0.69) | HDAC1HDAC7HDAC8HDAC6MLYCD | |
| SCHEMBL20941785 | 0.83 | HDAC1 (0.65) | HDAC1HDAC7HDAC8HDAC6MLYCD | |
| SCHEMBL10649341 | 0.80 | KMT2A (0.52) | HDAC1HDAC7HDAC8HDAC6CA1 | |
| SCHEMBL20941784 | 0.80 | HDAC1 (0.66) | HDAC1HDAC7HDAC8HDAC6MLYCD | |
| SCHEMBL17577313 | 0.80 | CA1 (0.56) | HDAC1HDAC7HDAC8HDAC6CA1 | |
| SCHEMBL26624042 | 0.80 | CA1 (0.56) | HDAC1HDAC7HDAC8HDAC6CA1 | |
| SCHEMBL7523309 | 0.79 | PDK1 (0.70) | HDAC1HDAC7HDAC8HDAC6TSHR | |
| SCHEMBL10648856 | 0.78 | HDAC1 (0.49) | HDAC1HDAC7HDAC8HDAC6CA1 | |
| SCHEMBL8846991 | 0.78 | HDAC1 (0.72) | HDAC1HDAC7HDAC8HDAC6CA1 | |
| SCHEMBL20941547 | 0.76 | HDAC1 (0.61) | HDAC1HDAC7HDAC8HDAC6MLYCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4764623-A | N-(1H-tetrazol-5-yl-alkylphenyl)polyfluoroalkanamides | AMERICAN HOME PRODUCTS CORPORATION (US) | 1988-08-16 | — | — | US | disclosed |