Salicylic Acid

Salicylic Acid

SCHEMBL106486

O=C(O)c1ccccc1O.[CaH2]

nearest known ligand 0.95

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHE

The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.95
KDM4E B2RXH2 6/20 0.95
HPGD P15428 6/20 0.95
SMN1; SMN2 Q16637 2/20 0.95
CA12 O43570 2/20 0.95
CA1 P00915 2/20 0.95
CA2 P00918 2/20 0.95
CA7 P43166 2/20 0.95
CA9 Q16790 2/20 0.95
CA14 Q9ULX7 2/20 0.95
HMGB1 P09429 1/20 0.95
CA4 P22748 1/20 0.95
CA6 P23280 1/20 0.95
NAPRT Q6XQN6 1/20 0.95
ALOX15 P16050 2/20 0.65
HSD17B10 Q99714 4/20 0.59
MAPT P10636 3/20 0.58
TSHR P16473 2/20 0.58
G6PD P11413 1/20 0.58
CASP7 P55210 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Salicylic Acid SCHEMBL27610514 1.00 ALDH1A1 (0.95) ALDH1A1KDM4EHPGDSMN1; SMN2CA12
Salicylic Acid SCHEMBL10669431 0.97 ALDH1A1 (0.90) ALDH1A1KDM4EHPGDSMN1; SMN2CA12
Salicylic Acid SCHEMBL503978 0.97 ALDH1A1 (0.90) ALDH1A1KDM4EHPGDSMN1; SMN2CA12
Salicylic Acid SCHEMBL28007729 0.97 ALDH1A1 (0.90) ALDH1A1KDM4EHPGDSMN1; SMN2CA12
Salicylic Acid SCHEMBL29360246 0.97 ALDH1A1 (1.00) ALDH1A1KDM4EHPGDSMN1; SMN2CA12
Salicylic Acid SCHEMBL29362663 0.97 ALDH1A1 (1.00) ALDH1A1KDM4EHPGDSMN1; SMN2CA12
Salicylic Acid SCHEMBL29606432 0.97 ALDH1A1 (1.00) ALDH1A1KDM4EHPGDSMN1; SMN2CA12
Salicylic Acid SCHEMBL17156443 0.97 ALDH1A1 (1.00) ALDH1A1KDM4EHPGDSMN1; SMN2CA12
Salicylic Acid SCHEMBL1509155 0.97 ALDH1A1 (1.00) ALDH1A1KDM4EHPGDSMN1; SMN2CA12
Salicylic Acid SCHEMBL1967 0.97 ALDH1A1 (1.00) ALDH1A1KDM4EHPGDSMN1; SMN2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 8037 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4748910-A1 LUBRICATING OIL COMPOSITION Idemitsu Kosan Co.,Ltd. (JP) 2026-05-27 EP claimed
CN-122095059-A Contains high content of C9Lubricant composition of di-substituted diphenylamine antioxidant 2026-05-26 CN claimed
WO-2026087620-A1 LUBRICANT COMPOSITIONS CONTAINING HIGH C9 DISUBSTITUTED DIPHENYLAMINE ANTIOXIDANT CONTENT INFINEUM INTERNATIONAL LIMITED (GB) 2026-04-30 WO claimed
US-20260109910-A1 Lubricant Compositions Containing High C9 Disubstituted Diphenylamine Antioxidant Content and Low Mono- and Tri-substituted Diphenylamine Antioxidant Content INFINEUM INTERNATTIONAL LTD (GB) 2026-04-23 US claimed
EP-4728001-A1 POLYAMIDE RECOVERY PROCESS Primpex-Plastiche Riunite Italiane Import-Export- S.p.a. (IT) 2026-04-22 EP claimed
US-12606766-B2 Multipurpose oxypyridinones and their functional use-4 INFINEUM INTERNATIONAL LIMITED (US) 2026-04-21 US claimed
US-12606764-B2 Lubricating oil compositions CHEVRON JAPAN LTD. 2026-04-21 US claimed
US-20260091072-A1 FOOD PRODUCTS COMPRISING OXALIC ACID- OR OXALATE-FREE INONOTUS OBLIQUUS EXTRACT THE BETTER FOR YOU COMPANY, LLC (US) 2026-04-02 US claimed
US-20260078315-A1 LUBRICATING OIL COMPOSITIONS FOR HYBRID ENGINES AND METHODS OF USE AND TESTING THEREOF INFINEUM INTERNATIONAL LIMITED 2026-03-19 US claimed
EP-4709825-A1 LOW DISPERSANT HIGH VI ENGINE OIL FOR IMPROVED FUEL ECONOMY Chevron Oronite Company LLC (US) 2026-03-18 EP claimed
EP-0225580-A2 Metal-containing lubricant compositions ETHYL CORPORATION (US) 1987-06-16 EP claimed
US-4664822-A OVERBASED COMPOUND CONTAINING COPPER AMOCO CORPORATION (US) 1987-05-12 US claimed
US-4539126-A Borated basic metal salt and lubricating oil composition SHELL OIL COMPANY (US) 1985-09-03 US claimed
EP-0036145-B1 AN ORALLY ADMINISTERED DRUG FORM COMPRISING A POLAR BIOACTIVE AGENT AND AN ADJUVANT INTERx RESEARCH CORPORATION (US) 1985-05-29 EP claimed
EP-0089136-A2 Oral hygiene products THE PROCTER & GAMBLE COMPANY (US) 1983-09-21 EP claimed
EP-0084910-A2 High dropping-point lithium-complex grease having improved anti-noise properties SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1983-08-03 EP claimed
US-4171558-A Cutting oil composition for processing cemented carbide skiving hob IDEMITSU KOSAN CO., LTD. (JP) 1979-10-23 US claimed
US-4141864-A ORTHOPEDICS, DENTISTRY, IN SITU LEACHABLE PARTICLES UNIVERSITY OF VIRGINIA ALUMNI PATENTS FOUNDATION (US) 1979-02-27 US claimed
US-3966903-A ALKYLENE CARBONATE SHISEIDO CO., LTD. (JA) 1976-06-29 US claimed
US-3964255-A Method of inflating an automobile passenger restraint bag SPECIALTY PRODUCTS DEVELOPMENT CORPORATION (US) 1976-06-22 US claimed