Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | NCF1 | P14598 | 2/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11037878 | 0.85 | NCF1 (0.41) | HTTALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL1131286 | 0.80 | NCF1 (0.50) | ALDH1A1MEN1KMT2AMAPTNCF1 | |
| SCHEMBL31498821 | 0.80 | NCF1 (0.50) | ALDH1A1MEN1KMT2AMAPTNCF1 | |
| SCHEMBL10675894 | 0.79 | MEN1 (0.41) | HTTALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL10511286 | 0.79 | HTT (0.63) | HTTALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL28691331 | 0.79 | MEN1 (0.44) | HTTALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL10767713 | 0.79 | ECE2 (0.42) | HTTALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL1602780 | 0.79 | HTR1B (0.44) | HTTALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL8712114 | 0.79 | HTT (0.68) | HTTALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL27666105 | 0.79 | SMN1; SMN2 (0.61) | HTTALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0254222-A2 | Quinolinoxy compounds, procedure for their synthesis and their application as antidotes | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-01-27 | — | — | EP | claimed |
| US-4236912-A | Quinolinyloxyphenoxy and quinolyinylthiophenoxy alkanoic acids and derivatives thereof and methods of herbicidal use | THE DOW CHEMICAL COMPANY (US) | 1980-12-02 | — | — | US | disclosed |
| US-4236912-A | Quinolinyloxyphenoxy and quinolyinylthiophenoxy alkanoic acids and derivatives thereof and methods of herbicidal use | THE DOW CHEMICAL COMPANY (US) | 1980-12-02 | — | — | US | disclosed |
| US-4236912-A | Quinolinyloxyphenoxy and quinolyinylthiophenoxy alkanoic acids and derivatives thereof and methods of herbicidal use | THE DOW CHEMICAL COMPANY (US) | 1980-12-02 | — | — | US | disclosed |