Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.44 |
| ▸ | RELA | Q04206 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | STAT1 | P42224 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.44 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.44 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10530386 | 0.94 | SLC2A1 (0.43) | SLC2A1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL10531308 | 0.93 | SLC2A1 (0.44) | SLC2A1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL10532337 | 0.92 | SLC2A1 (0.46) | SLC2A1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL10534419 | 0.92 | SLC2A1 (0.43) | SLC2A1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL10532566 | 0.87 | PDE4A (0.51) | NPC1RAB9AMAPTGAAALDH1A1 | |
| SCHEMBL10530460 | 0.87 | NPC1 (0.47) | SLC2A1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL10531240 | 0.86 | SLC2A1 (0.44) | SLC2A1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL10530438 | 0.83 | GUSB (0.40) | SMN1; SMN2NPBWR1ALDH1A1KDM4EHPGD | |
| SCHEMBL10531227 | 0.83 | NPC1 (0.45) | SLC2A1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL10531300 | 0.83 | SLC2A1 (0.46) | SLC2A1NPC1RAB9ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0263352-A1 | Imidazo-benzoxazinones, their preparation and medicaments containing these compounds | Dr. Karl Thomae GmbH (DE) | 1988-04-13 | — | — | EP | disclosed |