SCHEMBL10649999

SCHEMBL10649999

Nc1ncnc2c1ncn2[C@]1(CO)CCC[C@H]1O

nearest known ligand 0.51

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PI4K2A Q9BTU6 6/20 0.51
PI4KA P42356 5/20 0.51
PI4K2B Q8TCG2 5/20 0.51
PI4KB Q9UBF8 5/20 0.51
ADORA2A P29274 7/20 0.51
ADORA3 P0DMS8 5/20 0.51
SLC28A1 O00337 2/20 0.51
GMPS P49915 1/20 0.51
PRMT5 O14744 1/20 0.48
WDR77 Q9BQA1 1/20 0.48
SLC28A2 O43868 1/20 0.47
ADORA1 P30542 2/20 0.45
ADORA2B P29275 1/20 0.45
AHCY P23526 3/20 0.44
METTL3 Q86U44 1/20 0.43
METTL14 Q9HCE5 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10521569 0.87 PI4K2A (0.50) PI4K2API4KAPI4K2BPI4KBADORA2A
SCHEMBL9397052 0.72 PI4K2A (0.59) PI4K2API4KAPI4K2BPI4KBADORA2A
SCHEMBL27438888 0.72 PI4KA (0.67) PI4K2API4KAPI4K2BPI4KBADORA2A
SCHEMBL2298662 0.71 GMPS (0.63) PI4K2API4KAPI4K2BPI4KBADORA2A
SCHEMBL10647704 0.71 PI4K2A (0.51) PI4K2API4KAPI4K2BPI4KBADORA2A
SCHEMBL5821237 0.70 SLC28A1 (0.56) PI4K2API4KAPI4K2BPI4KBADORA2A
SCHEMBL646291 0.70 ADORA2A (0.56) PI4K2API4KAPI4K2BPI4KBADORA2A
SCHEMBL21591026 0.70 ADORA2A (0.53) PI4K2API4KAPI4K2BPI4KBADORA2A
SCHEMBL10427714 0.70 ADORA2A (0.50) PI4K2API4KAPI4K2BPI4KBADORA2A
SCHEMBL8094883 0.70 ADORA2A (0.50) PI4K2API4KAPI4K2BPI4KBADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0277599-A2 Fluorine containing cyclopentane derivatives and processes for their production ASAHI GLASS COMPANY LTD. (JP) 1988-08-10 EP disclosed