Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.50 |
| ▸ | SLC28A1 | O00337 | 2/20 | 0.50 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.47 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.47 |
| ▸ | GMPS | P49915 | 1/20 | 0.47 |
| ▸ | PI4K2A | Q9BTU6 | 5/20 | 0.47 |
| ▸ | PI4KA | P42356 | 4/20 | 0.47 |
| ▸ | PI4K2B | Q8TCG2 | 4/20 | 0.47 |
| ▸ | PI4KB | Q9UBF8 | 4/20 | 0.47 |
| ▸ | AHCY | P23526 | 3/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.44 |
| ▸ | ADA | P00813 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.42 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.42 |
| ▸ | GAPDH | P04406 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8108646 | 0.87 | ADORA2A (0.36) | ADORA2AADORA3SLC28A1PRMT5WDR77 | |
| SCHEMBL10427714 | 0.86 | ADORA2A (0.50) | ADORA2AADORA3SLC28A1PRMT5WDR77 | |
| SCHEMBL5180860 | 0.85 | ADORA2A (0.49) | ADORA2AADORA3SLC28A1PRMT5WDR77 | |
| SCHEMBL4745239 | 0.85 | PI4K2A (0.52) | ADORA2AADORA3SLC28A1PRMT5WDR77 | |
| SCHEMBL9446941 | 0.78 | ADORA2A (0.43) | ADORA2AADORA3SLC28A1PRMT5WDR77 | |
| SCHEMBL9956204 | 0.78 | SLC28A1 (0.57) | ADORA2AADORA3SLC28A1GMPSPI4K2A | |
| SCHEMBL2335292 | 0.78 | SLC28A1 (0.57) | ADORA2AADORA3SLC28A1GMPSPI4K2A | |
| SCHEMBL30382315 | 0.78 | ADORA2A (0.52) | ADORA2AADORA3SLC28A1PRMT5WDR77 | |
| SCHEMBL8104279 | 0.77 | PNP (0.47) | ADORA3MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL646291 | 0.76 | ADORA2A (0.56) | ADORA2AADORA3SLC28A1PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6040297-A | A THERAPEUTIC AGENTS TREATING TUMORS AND RETROVIRAL INFECTIONS INCLUDING HIV INFECTIONS | BIOSEARCH ITALIA, S.P.A. (IT) | 2000-03-21 | — | — | US | disclosed |