SCHEMBL10650198

SCHEMBL10650198

C=CC(C)(O)CCC(Cl)C(=C)C

nearest known ligand 0.46

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 3/20 0.46
MEN1 O00255 1/20 0.44
CYP3A4 P08684 1/20 0.44
KMT2A Q03164 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL942435 0.78 ALOX15 (0.47) ALOX15MEN1CYP3A4KMT2A
SCHEMBL12726637 0.78 ALOX15 (0.43) ALOX15MEN1CYP3A4KMT2A
SCHEMBL23953590 0.75 ALOX15 (0.41) ALOX15MEN1CYP3A4KMT2A
SCHEMBL9017164 0.74 GAA (0.39)
SCHEMBL8153609 0.73 ALOX15 (0.68) ALOX15MEN1CYP3A4KMT2A
SCHEMBL27529971 0.71 ALOX15 (0.61) ALOX15MEN1CYP3A4KMT2A
SCHEMBL996019 0.69 ALOX15 (0.48) ALOX15MEN1CYP3A4KMT2A
SCHEMBL26624407 0.69 ALOX15 (0.48) ALOX15MEN1CYP3A4KMT2A
SCHEMBL11779305 0.69 ALOX15 (0.53) ALOX15MEN1CYP3A4KMT2A
Linalool SCHEMBL10524667 0.69 ALOX15 (0.85) ALOX15MEN1CYP3A4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0131254-B1 PROCESS FOR THE PREPARATION OF SUBSTITUTED TETRAHYDROFURANES L. GIVAUDAN & CIE Société Anonyme (CH) 1988-05-25 EP claimed
EP-0131254-A2 Process for the preparation of substituted tetrahydrofuranes L. GIVAUDAN & CIE Société Anonyme (CH) 1985-01-16 EP claimed
EP-0131254-B1 PROCESS FOR THE PREPARATION OF SUBSTITUTED TETRAHYDROFURANES L. GIVAUDAN & CIE Société Anonyme (CH) 1988-05-25 EP disclosed
US-4510319-A ROGANOLEPTICS FRITZSCHE DODGE & OLCOTT INC. (US) 1985-04-09 US disclosed
EP-0131254-A2 Process for the preparation of substituted tetrahydrofuranes L. GIVAUDAN & CIE Société Anonyme (CH) 1985-01-16 EP disclosed