Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11516805 | 0.89 | SIGMAR1 (0.56) | L3MBTL1TDP1IDO1MAOAMAOB | |
| SCHEMBL3612659 | 0.85 | TSHR (0.50) | L3MBTL1TDP1IDO1TSHR | |
| SCHEMBL22029814 | 0.84 | IDO1 (0.67) | IDO1MAOAMAOBSIGMAR1FFAR1 | |
| SCHEMBL27770214 | 0.83 | TSHR (0.48) | L3MBTL1TDP1IDO1TSHR | |
| SCHEMBL9252659 | 0.82 | TSHR (0.50) | L3MBTL1TDP1SIGMAR1TSHRLTA4H | |
| SCHEMBL8236425 | 0.82 | IDO1 (0.48) | L3MBTL1TDP1IDO1MAOAMAOB | |
| SCHEMBL28308013 | 0.82 | TSHR (0.43) | L3MBTL1TDP1IDO1TSHR | |
| SCHEMBL4850679 | 0.80 | CETP (0.50) | L3MBTL1TDP1TSHRLTA4HEPHX2 | |
| SCHEMBL6704059 | 0.80 | CETP (0.50) | L3MBTL1TDP1TSHRLTA4HEPHX2 | |
| SCHEMBL9750038 | 0.80 | CETP (0.50) | L3MBTL1TDP1TSHRLTA4HEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0279681-A2 | Saturated heterocyclic carboxamide derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1988-08-24 | — | — | EP | disclosed |