SCHEMBL1065163

SCHEMBL1065163

N[C@@H](Cc1cnc(S)[nH]1)C(=O)O

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SLC7A5 Q01650 3/20 0.53
▸ CYP3A4 P08684 2/20 0.53
▸ SLC1A3 P43003 1/20 0.44
▸ HSD17B10 Q99714 2/20 0.41
▸ PKM P14618 2/20 0.41
▸ ALPI P09923 1/20 0.41
▸ PTGS1 P23219 1/20 0.41
▸ XIAP P98170 1/20 0.41
▸ GRIA2 P42262 4/20 0.39
▸ GRIA1 P42261 3/20 0.39
▸ GRIA4 P48058 3/20 0.39
▸ GRIA3 P42263 2/20 0.39
▸ GRIK5 Q16478 1/20 0.38
▸ USP2 O75604 2/20 0.38
▸ RGS12 O14924 1/20 0.38
▸ CYP2C9 P11712 1/20 0.38
▸ ALOX15 P16050 1/20 0.38
▸ NFKB1 P19838 1/20 0.38
▸ CASP1 P29466 1/20 0.38
▸ BRCA1 P38398 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14323788 1.00 SLC7A5 (0.53) SLC7A5CYP3A4SLC1A3HSD17B10PKM
SCHEMBL5284026 1.00 SLC7A5 (0.53) SLC7A5CYP3A4SLC1A3HSD17B10PKM
SCHEMBL1865520 0.98 SLC7A5 (0.51) SLC7A5CYP3A4SLC1A3HSD17B10PKM
SCHEMBL1869348 0.98 SLC7A5 (0.51) SLC7A5CYP3A4SLC1A3HSD17B10PKM
SCHEMBL1866100 0.98 SLC7A5 (0.51) SLC7A5CYP3A4SLC1A3HSD17B10PKM
SCHEMBL1868482 0.98 SLC7A5 (0.51) SLC7A5CYP3A4SLC1A3HSD17B10PKM
SCHEMBL1865514 0.98 SLC7A5 (0.51) SLC7A5CYP3A4SLC1A3HSD17B10PKM
Ammonia Solution, Strong SCHEMBL1864550 0.98 SLC7A5 (0.51) SLC7A5CYP3A4SLC1A3HSD17B10PKM
SCHEMBL1868579 0.98 SLC7A5 (0.51) SLC7A5CYP3A4SLC1A3HSD17B10PKM
SCHEMBL13095827 0.81 SLC7A5 (0.54) SLC7A5CYP3A4SLC1A3HSD17B10PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 253 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12428447-B2 Peptide-based non-proteinaceous cargo delivery FELDAN BIO INC. (CA) 2025-09-30 — — US claimed
CN-119015131-A Multifunctional hard tissue treating agent based on sulfhydryl and carboxylic acid group structural compound and application thereof 浙江大学 2024-11-26 — — CN claimed
US-20240197896-A1 SYNTHETIC PEPTIDE SHUTTLE AGENT BIOCONJUGATES FOR INTRACELLULAR CARGO DELIVERY FELDAN BIO INC. (CA) 2024-06-20 — — US claimed
CN-117750978-A Synthetic peptide shuttle bioconjugates for intracellular cargo delivery 费尔丹生物公司 2024-03-22 — — CN claimed
EP-4313159-A1 SYNTHETIC PEPTIDE SHUTTLE AGENT BIOCONJUGATES FOR INTRACELLULAR CARGO DELIVERY Feldan Bio Inc. (CA) 2024-02-07 — — EP claimed
US-20230399661-A1 SHUTTLE AGENT PEPTIDES OF MINIMAL LENGTH AND VARIANTS THEREOF ADAPTED FOR TRANSDUCTION OF CAS9-RNP AND OTHER NUCLEOPROTEIN CARGOS FELDAN BIO INC. (CA) 2023-12-14 — — US claimed
US-20230383291-A1 PEPTIDE-BASED TRANSDUCTION OF NON-ANIONIC POLYNUCLEOTIDE ANALOGS FOR GENE EXPRESSION MODULATION FELDAN BIO INC. (CA) 2023-11-30 — — US claimed
EP-4232590-A1 SHUTTLE AGENT PEPTIDES OF MINIMAL LENGTH AND VARIANTS THEREOF ADAPTED FOR TRANSDUCTION OF CAS9-RNP AND OTHER NUCLEOPROTEIN CARGOS Feldan Bio Inc. (CA) 2023-08-30 — — EP claimed
EP-4229207-A1 PEPTIDE-BASED TRANSDUCTION OF NON-ANIONIC POLYNUCLEOTIDE ANALOGS FOR GENE EXPRESSION MODULATION Feldan Bio Inc. (CA) 2023-08-23 — — EP claimed
CN-116615227-A Minimum length shuttle peptide suitable for transduction of Cas9-RNP and other nucleoprotein loads and variants thereof 费尔丹生物公司 2023-08-18 — — CN claimed
WO-2011042478-A1 METHOD FOR THE SYNTHESIS OF 2-THIOHISTIDINE AND THE LIKE TETRAHEDRON (FR) 2011-04-14 — — WO claimed
US-20080161377-A1 Use of L-2-thiohistidine or one of its derivatives as a depigmenting agent in cosmetics LVMH RECHERCHE (FR) 2008-07-03 — — US claimed
EP-1938793-A2 Use in cosmetics of L-2-thiohistidine or one of its derivatives as a depigmentation agent LVMH RECHERCHE (FR) 2008-07-02 — — EP claimed
US-6727076-B2 UTILIZES A GEL FORMING MATRIX FOR THE RAPID SCREENING OF CLINICAL AND ENVIRONMENTAL CULTURES BIOLOG, INC. 2004-04-27 — — US claimed
US-6472201-B1 GROWING AND TESTING MICROORGANISMS IN A MULTITEST FORMAT WHICH UTILIZES A GEL FORMING MATRIX FOR THE RAPID SCREENING OF CLINICAL AND ENVIRONMENTAL CULTURES BIOLOG, INC. 2002-10-29 — — US claimed
US-5756650-A COMPOSITION COMPRISING POLYAMIC ACID, CURE ACCELERATOR SELECTED FROM GROUP CONSISTING OF NITROGEN-CONTAINING HETEROCYCLIC COMPOUND, AMINO ACID COMPOUND, AROMATIC COMPOUND HAVING TWO OR MORE HYDROXYL GROUPS KABUSHIKI KAISHA TOSHIBA (JP) 1998-05-26 — — US claimed
EP-0498268-A2 5-Oxo-L-proline derivatives and pharmaceutical use thereof POLI INDUSTRIA CHIMICA S.p.A. (IT) 1992-08-12 — — EP claimed
EP-0483426-A1 Thiol heterocyclic deodorant composition and method of deodorization THE PROCTER & GAMBLE COMPANY (US) 1992-05-06 — — EP claimed
US-4662905-A REACTION PRODUCT OF COPPER SALT AND AN IMIDAZOLE, PYRAZOLE, TRIAZOLE, OR TETRAZOLE Itaru Todoriki, Director of Agency of Industrial Science and Technology (JP) 1987-05-05 — — US claimed
EP-0142387-A1 Process for the preparation of vaccines specific for LH and HCG and process for their detection ANDA BIOLOGICALS (FR) 1985-05-22 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240197896-A1 SYNTHETIC PEPTIDE SHUTTLE AGENT BIOCONJUGATES FOR INTRACELLULAR CARGO DELIVERY SCAMP2, SLC7A1, NUMA1 SLC7A5 35/4885CYP3A4 4818/4885SLC1A3 551/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback