Sugi Predict

Sugi Predict / Targets / NUMA1

NUMA1

Nuclear mitotic apparatus protein 1 · Q14980 · NUMA1 on Sugi Atlas →

0 patent compounds predicted against NUMA1, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to NUMA1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Genotoxicity Assessment of Dental Implants in Gingival Epithelial Cells PHASE3UNKNOWN
Phase II Trial of Lonafarnib (a Farnesyltransferase Inhibitor) for Progeria PHASE2COMPLETED
Phase I Study of Oral BAY 1217389 in Combination With Intravenous Paclitaxel PHASE1COMPLETED
Study of ABT-751 in Patients With Refractory Hematologic Malignancies PHASE1COMPLETED
Phase I Study to Assess the Safety, Pharmacokinetics, & Pharmacodynamics of GSK923295 in Subjects w/ Refractory Cancer PHASE1COMPLETED
Importance of the Microtubule Cytoskeleton in Oocyte Competence nanCOMPLETED
Role of the Nuclear Pore Component RANBP2 in Inflammatory Responses to Viral Infections nanCOMPLETED
Post Market Surveillance & Post Market Clinical Follow up, International, Medical Registry to Confirm the Safety and the Performance of the Anecova Intra Uterine Culture Device nanWITHDRAWN
The Contribution of Optical Mapping to the Characterization of Chromosomal Rearrangements in Patients With Neurodevelopmental Disorders nanRECRUITING
Efect of Quinoa and Flaxseed in Cititoxicity and Glicemic Control in Metabolic Syndrome Patients nanUNKNOWN
The Role of Maspin in Colorectal Carcinoma, an Immunohistochemical Study nanNOT_YET_RECRUITING
Impact of Weight Loss on the Human Sperm Epitranscriptome nanACTIVE_NOT_RECRUITING
Genetic Bases of Neuroendocrine Neoplasms in Mexican Patients nanRECRUITING
A Clinical Study on the Efficacy and Safety of Methotrexate (MTX) or Thiotepa (for MTX Intolerance) or Temozolomide (TMZ) Combined With Orelabrutinib and Selinexor in Relapsed/Refractory Primary or Secondary Central Nervous System Lymphoma（SELINA） nanRECRUITING
Better Delineation of CDK13 Related Phenotype and Epigenetic Signature. nanUNKNOWN
The Roles of Neutrophil Elastase in Lung Cancer nanUNKNOWN
Nuclear Myosin VI - a Therapeutic Target in Breast Cancer nanUNKNOWN
Genetics of Neonatal Encephalopathy and Related Disorders nanRECRUITING
PCM1-JAK2 in Therapy Related Neoplasms nanUNKNOWN
Quantitative Assessment of the Etiologies of Megalencephaly Associated With a Detectable Tumor Risk nanNOT_YET_RECRUITING
Multicenter Phenotype-Genotype Analysis of Vascular Stains to Optimize Treatment Utilizing Optical Coherence Tomography nanACTIVE_NOT_RECRUITING
Biological Aging Hallmarks-Guided Integrative TCM and Conventional Medicine in Post-Treatment Unexplained Female Infertility nanRECRUITING
Study of the Effect of Innate on the Inflammatory Response to Endotoxin nanRECRUITING
The Relation of Microtubule-Associated Protein 2 and Cell Migration nanUNKNOWN
Whole-genome Sequencing Study in Patients With Diminished Ovarian Reserve nanUNKNOWN
Prenatal Cell-free DNA Screening in Pregnancies With Diverse Genetic Risk Profiles Utilizing Targeted and Whole-exome Sequencing nanNOT_YET_RECRUITING
The Natural History of Mitochondrial Diseases nanRECRUITING
The Impact of Mitochondrial Dysfunction on Human Bone Cell Metabolism and Remodelling nanACTIVE_NOT_RECRUITING
Validation of Optical Genome Mapping for the Identification of Constitutional Genomic Variants in a Postnatal Cohort nanUNKNOWN
Natural History Study of Mitochondrial Myopathy nanRECRUITING

Related proteins — ESM-2 sequence neighbours (a NUMA1 binder may also engage these)

ProteinNameSimilarity
Q8VDC1 — 0.998 Q8VDC1 →
Q9BV73 — 0.997 Q9BV73 →
Q8CJ40 — 0.997 Q8CJ40 →
E9Q7G0 — 0.996 E9Q7G0 →
Q92805 — 0.995 Q92805 →
IKBKG NF-kappa-B essential modulator 0.994 landscape →
Q13439 — 0.994 Q13439 →
Q6ZU80 — 0.994 Q6ZU80 →
Q5U4E6 — 0.994 Q5U4E6 →
Q29RS0 — 0.994 Q29RS0 →
Q60952 — 0.994 Q60952 →
Q8N998 — 0.994 Q8N998 →
Q91VW5 — 0.993 Q91VW5 →
Q9CW79 — 0.993 Q9CW79 →
Q8NB25 — 0.993 Q8NB25 →
Q7YS99 — 0.993 Q7YS99 →
P97779 — 0.992 P97779 →
B9V5F5 — 0.992 B9V5F5 →
Q8NCX0 — 0.992 Q8NCX0 →
Q2TAC2 — 0.992 Q2TAC2 →
Q8CDI7 — 0.992 Q8CDI7 →
O55156 — 0.992 O55156 →
Q6NZW0 — 0.991 Q6NZW0 →
Q9ULE4 — 0.991 Q9ULE4 →
Q6TMG5 — 0.990 Q6TMG5 →
Q5ZKK5 — 0.990 Q5ZKK5 →
A7MD70 — 0.990 A7MD70 →
Q9BQS8 — 0.990 Q9BQS8 →
Q9Z221 — 0.990 Q9Z221 →
Q502I3 — 0.990 Q502I3 →