Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.68 |
| ▸ | MAPT | P10636 | 1/20 | 0.68 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.49 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19876816 | 0.97 | SMN1; SMN2 (0.69) | SMN1; SMN2TDP1MAPTLIN28AKMT2A | |
| SCHEMBL22749407 | 0.94 | SMN1; SMN2 (0.60) | SMN1; SMN2TDP1MAPTLIN28AKMT2A | |
| SCHEMBL23495444 | 0.91 | SMN1; SMN2 (0.56) | SMN1; SMN2TDP1MAPTLIN28AKMT2A | |
| SCHEMBL5062633 | 0.90 | SMN1; SMN2 (0.64) | SMN1; SMN2TDP1MAPTLIN28AKMT2A | |
| SCHEMBL12762776 | 0.89 | SMN1; SMN2 (0.62) | SMN1; SMN2TDP1MAPTLIN28AKMT2A | |
| SCHEMBL7949662 | 0.88 | SMN1; SMN2 (0.60) | SMN1; SMN2TDP1MAPTLIN28AKMT2A | |
| SCHEMBL1517940 | 0.88 | SMN1; SMN2 (0.60) | SMN1; SMN2TDP1MAPTLIN28AKMT2A | |
| SCHEMBL19876826 | 0.85 | TDP1 (0.71) | SMN1; SMN2TDP1MAPTLIN28AKMT2A | |
| SCHEMBL29574935 | 0.85 | SMN1; SMN2 (0.71) | SMN1; SMN2TDP1MAPTLIN28AKMT2A | |
| SCHEMBL8200516 | 0.85 | SMN1; SMN2 (0.71) | SMN1; SMN2TDP1MAPTLIN28AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12625144-B2 | Chemoselective sensitivity booster for tagging a peptide, peptide conjugate, or similar reactive molecule | Indian Institute Of Science Education And Research Bhopal (IN) | 2026-05-12 | — | — | US | disclosed |
| US-20220299521-A1 | CHEMOSELECTIVE SENSITIVITY BOOSTER FOR TAGGING A PEPTIDE, PEPTIDE CONJUGATE, OR SIMILAR REACTIVE MOLECULE | Indian Institute Of Science Education And Research Bhopal (IN) | 2022-09-22 | — | — | US | disclosed |
| WO-2020245843-A1 | CHEMOSELECTIVE SENSITIVITY BOOSTER FOR TAGGING A PEPTIDE, PEPTIDE CONJUGATE, OR SIMILAR REACTIVE MOLECULE | Indian Institute Of Science Education And Research Bhopal (IN) | 2020-12-10 | — | — | WO | disclosed |
| US-10039845-B2 | Labeled inhibitors of prostate specific membrane antigen (PSMA) biological evaluation, and use of imaging agents | THE JOHNS HOPKINS UNIVERSITY (US) | 2018-08-07 | — | — | US | disclosed |
| US-20180085478-A1 | LABELED INHIBITORS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA) BIOLOGICAL EVALUATION, AND USE OF IMAGING AGENTS | THE JOHNS HOPKINS UNIVERSITY (US) | 2018-03-29 | — | — | US | disclosed |
| US-9694091-B2 | Labeled inhibitors of prostate specific membrane antigen (PSMA) biological evaluation, and use of imaging agents | THE JOHNS HOPKINS UNIVERSITY (US) | 2017-07-04 | — | — | US | disclosed |
| EP-2963017-A1 | TECHNETIUM-DIPYRIDINE COMPLEXES, AND METHODS OF USE THEREOF | Molecular Insight Pharmaceuticals, Inc. (US) | 2016-01-06 | — | — | EP | disclosed |
| EP-1482985-B1 | TECHNETIUM-DIPYRIDINE COMPLEXES, AND METHODS OF USE THEREOF | MOLECULAR INSIGHT PHARM INC (US) | 2015-12-23 | — | — | EP | disclosed |
| US-20150246144-A1 | LABELED INHIBITORS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA) BIOLOGICAL EVALUATION, AND USE OF IMAGING AGENTS | THE JOHNS HOPKINS UNIVERSITY (US) | 2015-09-03 | — | — | US | disclosed |
| US-9044468-B2 | Labeled inhibitors of prostate specific membrane antigen (PSMA), biological evaluation, and use as imaging agents | THE JOHNS HOPKINS UNIVERSITY (US) | 2015-06-02 | — | — | US | disclosed |
| US-20090023787-A1 | TECHNETIUM-DIPYRIDINE COMPLEXES, AND METHODS OF USE THEREOF | MOLECULAR INSIGHT PHARMACEUTICALS, INC. | 2009-01-22 | — | — | US | disclosed |
| US-7381399-B2 | Technetium-dipyridine complexes, and methods of use thereof | MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) | 2008-06-03 | — | — | US | disclosed |
| US-20080025915-A1 | Technetium-And Rhenium-Bis (Heteroaryl) Complexes, And Methods Of Use Thereof | CITIZENS BANK, N.A. | 2008-01-31 | — | — | US | disclosed |
| EP-1713515-A1 | TECHNETIUM- AND RHENIUM-BIS(HETEROARYL) COMPLEXES, AND METHODS OF USE THEREOF | Molecular Insight Pharmaceuticals, Inc. (US) | 2006-10-25 | — | — | EP | disclosed |
| EP-1482985-A4 | TECHNETIUM-DIPYRIDINE COMPLEXES, AND METHODS OF USE THEREOF | MOLECULAR INSIGHT PHARM INC (US) | 2006-06-28 | — | — | EP | disclosed |
| US-20060034758-A1 | Technetium- and rhenium-bis(heteroaryl) complexes, and methods of use thereof | MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) | 2006-02-16 | — | — | US | disclosed |
| WO-2005079865-A1 | TECHNETIUM- AND RHENIUM-BIS(HETEROARYL) COMPLEXES, AND METHODS OF USE THEREOF | MOLECULAR INSIGHT PHARMACEUTICALS (US) | 2005-09-01 | — | — | WO | disclosed |
| EP-1482985-A2 | TECHNETIUM-DIPYRIDINE COMPLEXES, AND METHODS OF USE THEREOF | Biostream, Inc. (US) | 2004-12-08 | — | — | EP | disclosed |
| US-20030235843-A1 | Technetium-depyridine complexes, and methods of use thereof | CITIZENS BANK, N.A. | 2003-12-25 | — | — | US | disclosed |
| WO-2003077727-A2 | TECHNETIUM-DIPYRIDINE COMPLEXES, AND METHODS OF USE THEREOF | BIOSTREAM, INC. (US) | 2003-09-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180085478-A1 | LABELED INHIBITORS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA) BIOLOGICAL EVALUATION, AND USE OF IMAGING AGENTS | FOLH1, KLK3, PHOSPHO1 | SMN1; SMN2 4613/4885TDP1 3381/4885MAPT 1350/4885 |
| US-20220299521-A1 | CHEMOSELECTIVE SENSITIVITY BOOSTER FOR TAGGING A PEPTIDE, PEPTIDE CONJUGATE, OR SIMILAR REACTIVE MOLECULE | PTMS, PA2G4, MAX | SMN1; SMN2 3108/4885TDP1 4554/4885MAPT 3491/4885 |
| US-20030235843-A1 | Technetium-depyridine complexes, and methods of use thereof | SLC7A5, DNPEP, SLC7A1 | SMN1; SMN2 4210/4885TDP1 808/4885MAPT 2801/4885 |
| US-10039845-B2 | Labeled inhibitors of prostate specific membrane antigen (PSMA) biological evaluation, and use of imaging agents | FOLH1, KLK3, PHOSPHO1 | SMN1; SMN2 4613/4885TDP1 3381/4885MAPT 1350/4885 |
| US-20150246144-A1 | LABELED INHIBITORS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA) BIOLOGICAL EVALUATION, AND USE OF IMAGING AGENTS | FOLH1, KLK3, PHOSPHO1 | SMN1; SMN2 4613/4885TDP1 3381/4885MAPT 1350/4885 |
| US-20060034758-A1 | Technetium- and rhenium-bis(heteroaryl) complexes, and methods of use thereof | SLC7A5, RAB35, AADAT | SMN1; SMN2 4259/4885TDP1 2995/4885MAPT 3876/4885 |
| US-12625144-B2 | Chemoselective sensitivity booster for tagging a peptide, peptide conjugate, or similar reactive molecule | DPYSL3, CD2BP2, PTMS | SMN1; SMN2 3324/4885TDP1 2841/4885MAPT 3019/4885 |
| US-20090023787-A1 | TECHNETIUM-DIPYRIDINE COMPLEXES, AND METHODS OF USE THEREOF | SLC7A5, SLC7A1, AADAT | SMN1; SMN2 4102/4885TDP1 1026/4885MAPT 2979/4885 |
| US-20080025915-A1 | Technetium-And Rhenium-Bis (Heteroaryl) Complexes, And Methods Of Use Thereof | SLC7A5, RAB35, AADAT | SMN1; SMN2 4259/4885TDP1 2995/4885MAPT 3876/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.