Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 14/20 | 0.47 |
| ▸ | CYSLTR1 | Q9Y271 | 14/20 | 0.47 |
| ▸ | LTB4R | Q15722 | 4/20 | 0.46 |
| ▸ | LTB4R2 | Q9NPC1 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | PDE5A | O76074 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10639132 | 0.92 | PPARG (0.46) | CYSLTR2CYSLTR1LTB4RLTB4R2LMNA | |
| Sc-39070 SCHEMBL9119171 | 0.92 | CYSLTR2 (0.56) | CYSLTR2CYSLTR1LTB4RLTB4R2LMNA | |
| SCHEMBL10407892 | 0.88 | CYSLTR2 (0.58) | CYSLTR2CYSLTR1LTB4RLTB4R2LMNA | |
| SCHEMBL10504382 | 0.86 | LTB4R (0.47) | CYSLTR2CYSLTR1LTB4RLTB4R2LMNA | |
| SCHEMBL9821758 | 0.86 | LTB4R (0.53) | CYSLTR2CYSLTR1LTB4RLTB4R2 | |
| SCHEMBL10344123 | 0.86 | CYSLTR2 (0.58) | CYSLTR2CYSLTR1LTB4RLTB4R2LMNA | |
| SCHEMBL10407815 | 0.85 | LTB4R (0.49) | CYSLTR2CYSLTR1LTB4RLTB4R2LMNA | |
| SCHEMBL10505028 | 0.84 | LTB4R (0.47) | CYSLTR2CYSLTR1LTB4RLTB4R2LMNA | |
| SCHEMBL10743355 | 0.84 | LTB4R (0.49) | CYSLTR2CYSLTR1LTB4RLTB4R2LMNA | |
| SCHEMBL9821796 | 0.84 | PPARG (0.54) | CYSLTR2CYSLTR1LTB4RLTB4R2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0254329-A1 | Substituted dihydrobenzopyranones | G.D. Searle & Co. (US) | 1988-01-27 | — | — | EP | disclosed |