Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | F2RL3 | Q96RI0 | 2/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | F9 | P00740 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10933439 | 0.91 | F2RL3 (0.56) | LMNARECQLF2RL3ADORA3ADORA2A | |
| SCHEMBL10649757 | 0.89 | F2RL3 (0.54) | LMNARECQLF2RL3ADORA3ADORA2A | |
| SCHEMBL4497419 | 0.87 | LMNA (0.57) | LMNARECQLF2RL3ADORA3KMT2A | |
| SCHEMBL10651238 | 0.87 | LMNA (0.71) | LMNARECQLADORA3ADORA2AADORA1 | |
| SCHEMBL10652188 | 0.85 | LMNA (0.69) | LMNARECQLADORA3ADORA2AADORA1 | |
| SCHEMBL29902834 | 0.82 | LMNA (0.68) | LMNARECQLF2RL3ADORA3ADORA2A | |
| SCHEMBL10649682 | 0.82 | LMNA (0.68) | LMNARECQLF2RL3ADORA3ADORA2A | |
| SCHEMBL10648834 | 0.81 | LMNA (0.66) | LMNARECQLF2RL3ADORA3ADORA2A | |
| SCHEMBL29902852 | 0.81 | LMNA (0.66) | LMNARECQLF2RL3ADORA3ADORA2A | |
| SCHEMBL10506009 | 0.81 | CA12 (0.52) | F2RL3ADORA3ADORA2AADORA1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0187387-B1 | BENZOFURAN DERIVATIVE, PROCESS FOR PREPARING THE SAME AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Kaken Pharmaceutical Co., Ltd. (JP) | 1988-09-28 | — | — | EP | disclosed |
| EP-0187387-A1 | Benzofuran derivative, process for preparing the same and pharmaceutical composition containing the same | Kaken Pharmaceutical Co., Ltd. (JP) | 1986-07-16 | — | — | EP | disclosed |