Hexaethylene Glycol

Hexaethylene Glycol

SCHEMBL1065217

NP(O)O.OCCOCCOCCOCCOCCOCCO

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.69
KMT2A Q03164 3/20 0.69
TSHR P16473 2/20 0.62
MAPK1 P28482 1/20 0.62
THRB P10828 1/20 0.44
HTT P42858 1/20 0.44
MAPT P10636 1/20 0.44
ALDH1A1 P00352 1/20 0.43
APP P05067 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pentaethylene Glycol SCHEMBL1115918 1.00 MEN1 (0.69) MEN1KMT2ATSHRMAPK1THRB
Tetraethylene Glycol SCHEMBL8446693 1.00 MEN1 (0.69) MEN1KMT2ATSHRMAPK1THRB
Triethylene Glycol SCHEMBL9056861 1.00 MEN1 (0.69) MEN1KMT2ATSHRMAPK1THRB
Tetraethylene Glycol SCHEMBL5481290 0.87 MEN1 (0.79) MEN1KMT2ATSHRMAPK1THRB
Triethylene Glycol SCHEMBL6267958 0.87 MEN1 (0.79) MEN1KMT2ATSHRMAPK1THRB
Triethylene Glycol SCHEMBL3701476 0.87 MEN1 (0.79) MEN1KMT2ATSHRMAPK1THRB
Tetraethylene Glycol SCHEMBL16424033 0.87 MEN1 (0.92) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL844249 0.84 MEN1 (0.55) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL30688068 0.84 MEN1 (0.55) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL1115916 0.84 MEN1 (0.55) MEN1KMT2ATSHRMAPK1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102380098-B Combination therapy for the treatment of ocular neovascular disorders OPHTHOTECH CORP 2015-07-22 CN claimed
CN-102813923-B Combination therapy for the treatment of ocular neovascular disorders OPHTHOTECH CORP 2015-04-01 CN claimed
CN-1934255-B Combination therapy for the treatment of ocular neovascular diseases OSI EYETECH INC 2012-07-11 CN claimed
CN-102380098-A Combination therapy for the treatment of ocular neovascular disorders EYETECH PHARMACEUTICALS INC 2012-03-21 CN claimed
US-7879993-B2 Covalently linking PDGF Nucleic Acid Ligand with a Non-Immunogenic, High Molecular Weight Compound or Lipophilic Compound to form a Complex; diagnostic and therapeutic agent; improving pharmacokinetic properties GILEAD SCIENCES, INC. (US) 2011-02-01 US claimed
US-20080207883-A1 Platelet Derived Growth Factor (PDGF) Nucleic Acid Ligand Complexes GILEAD SCIENCES, INC. (US) 2008-08-28 US claimed
CN-122029282-A Novel aptamers to EphA2 (hepaplatin receptor 2 a) 阿普塔德尔治疗公司 2026-05-12 CN disclosed
US-20250289957-A1 POLYMERIC TANDEM DYES WITH LINKER GROUPS SONY GROUP CORP (JP) 2025-09-18 US disclosed
US-20250243250-A1 THERAPEUTIC NANOCONJUGATES AND USES THEREOF UNIV AUTÒNOMA DE BARCELONA UAB (ES) 2025-07-31 US disclosed
US-12359071-B2 Polymeric tandem dyes with linker groups Sony Group Corporation (JP) 2025-07-15 US disclosed
US-20250188455-A1 LIPOPHILIC OLIGONUCLEOTIDE CONJUGATES VANDERBILT UNIVERSITY 2025-06-12 US disclosed
US-12319817-B2 Polymeric tandem dyes with linker groups Sony Group Corporation (JP) 2025-06-03 US disclosed
US-12275851-B2 Polymeric tandem dyes with linker groups Sony Group Corporation (JP) 2025-04-15 US disclosed
US-6306643-B1 NUCLEOTIDE SEQUENCE SUPPORT; FOR USE IN MONITORING GENE EXPRESSION; FOR USE IN LINKAGE AND SEQUENCE ANALYSIS AFFYMETRIX, INC. 2001-10-23 US disclosed
EP-1108062-A1 USE OF POOLED PROBES IN GENETIC ANALYSIS Affymetrix, Inc. (US) 2001-06-20 EP disclosed
US-6229002-B1 COMPLEX OF NUCLEIC ACID WHICH BINDS TO PLATELET DERIVED GROWTH FACTOR AND NONIMMUNOGENIC, HIGH MOLECULAR WEIGHT COMPOUND; FOR TARGETED DIAGNOSTIC AND THERAPY; ANTICARCINOGENIC AGENTS; CARDIOVASCULAR DISORDERS; KIDNEY DISEASE NEXSTAR PHARMACEUTICLAS, INC. 2001-05-08 US disclosed
WO-2000011223-A9 USE OF POOLED PROBES IN GENETIC ANALYSIS AFFYMETRIX INC (US) 2001-04-12 WO disclosed
EP-1042348-A1 PLATELET DERIVED GROWTH FACTOR (PDGF) NUCLEIC ACID LIGAND COMPLEXES NeXstar Pharmaceuticals, Inc. (US) 2000-10-11 EP disclosed
WO-2000011223-A1 USE OF POOLED PROBES IN GENETIC ANALYSIS AFFYMETRIX, INC. (US) 2000-03-02 WO disclosed
WO-1999031119-A1 PLATELET DERIVED GROWTH FACTOR (PDGF) NUCLEIC ACID LIGAND COMPLEXES NEXSTAR PHARMACEUTICALS, INC. (US) 1999-06-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12359071-B2 Polymeric tandem dyes with linker groups CHRM1, IK, TMT1A MEN1 552/4885KMT2A 1968/4885TSHR 644/4885
US-20080207883-A1 Platelet Derived Growth Factor (PDGF) Nucleic Acid Ligand Complexes PDGFA, PDGFRA, PDGFRB MEN1 3941/4885KMT2A 2936/4885TSHR 2373/4885
US-20250289957-A1 POLYMERIC TANDEM DYES WITH LINKER GROUPS CHRM1, IK, TMT1A MEN1 552/4885KMT2A 1968/4885TSHR 644/4885
US-12319817-B2 Polymeric tandem dyes with linker groups CHRM1, MTCL3, TMT1A MEN1 424/4885KMT2A 2441/4885TSHR 409/4885
US-12275851-B2 Polymeric tandem dyes with linker groups CHRM1, MTCL3, TMT1A MEN1 434/4885KMT2A 2444/4885TSHR 411/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.