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PDGFA

Platelet-derived growth factor subunit A · P04085 · PDGFA on Sugi Atlas →

162 patent compounds predicted against PDGFA, 154 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL823682 SCHEMBL823682 1.00 1/20
SCHEMBL22567120 SCHEMBL22567120 0.90 1/20
SCHEMBL29525367 SCHEMBL29525367 0.83 1/20
SCHEMBL22275546 SCHEMBL22275546 0.82 1/20
SCHEMBL823546 SCHEMBL823546 0.81 1/20
SCHEMBL823638 SCHEMBL823638 0.81 1/20
SCHEMBL28496454 SCHEMBL28496454 0.81 1/20
SCHEMBL29525771 SCHEMBL29525771 0.79 1/20
SCHEMBL826332 SCHEMBL826332 0.78 1/20
SCHEMBL823554 SCHEMBL823554 0.78 1/20
SCHEMBL25412537 SCHEMBL25412537 0.74 1/20
SCHEMBL30358255 SCHEMBL30358255 0.74 1/20
SCHEMBL15288697 SCHEMBL15288697 0.73 1/20
SCHEMBL823624 SCHEMBL823624 0.72 1/20
SCHEMBL2453182 SCHEMBL2453182 0.72 1/20
SCHEMBL826462 SCHEMBL826462 0.71 1/20
SCHEMBL25245245 SCHEMBL25245245 0.71 1/20
SCHEMBL29025431 SCHEMBL29025431 0.70 1/20
SCHEMBL29025422 SCHEMBL29025422 0.69 1/20
SCHEMBL823633 SCHEMBL823633 0.66 1/20

Clinical trials — most relevant to PDGFA by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Platelet Rich Plasma in Corneal Surface Diseases PHASE3UNKNOWN
Evaluation of Platelet Rich Fibrin Matrix as Regenerative Material in Intraosseous Defects PHASE3COMPLETED
The Effect of PRP on Wound Healing in High Risk Patients Undergoing Abdominal Hysterectomy PHASE2/PHASE3UNKNOWN
Platelet Rich Plasma in Treatment of Melasma PHASE3UNKNOWN
An Open-label Phase II Study With SUTENT in Patients Suffering From Hormone Refractory Prostate Cancer PHASE2COMPLETED
SUTENT (SUNITINIB, SU11248)in Patients With Recurrent or Progressive Glioblastoma Multiforme PHASE2UNKNOWN
Nitroglycerin Plus Intracranial Radiotherapy for Brain Metastases in NSCLC Patients PHASE2COMPLETED
Treatment Outcome of Autologous PRP Versus Conventional Therapy Among Patients With Chronic Venous Leg Ulcers PHASE1COMPLETED
Combined LASERs and PRP for Postacne Scars nanCOMPLETED
Platelet-Rich Plasma for Partial Rotator Cuff Tears nanNOT_YET_RECRUITING
Study to Assess Efficacy of Platelet-Rich Plasma in Androgenetic Alopecia nanUNKNOWN
Management of Retinitis Pigmentosa Via Electromagnetic Stimulation and Platelet Rich Plasma nanCOMPLETED
Platelet Rich Plasma for Uterine Scar nanRECRUITING
Platelet Rich Plasma for Treatment of Facial Photoaging: A Double-blind, Randomized, Split-face Study nanUNKNOWN
Experimental Study on the Use of Intrauterine Infusion of Autologous Platelet-rich Plasma (PRGF-IUI) in Patients With Recurrent Implantation Failure and/or Refractory Thin Endometrium nanNOT_YET_RECRUITING
Effects of Subtenon-injected Autologous Platelet-rich Plasma on Visual Functions in Eyes With Retinitis Pigmentosa nanCOMPLETED
Efficacy of Platelet-Rich Plasma Therapy for Androgenetic Alopecia: A Systematic Review and Meta-analysis nanUNKNOWN
Platelet Rich Plasma Versus Placebo for the Treatment of Greater Trochanteric Pain Syndrome (HiPPO Trial) nanCOMPLETED
PRP Versus PRF Versus Conventional Treatment in Chronic Non-healing Skin Ulcers nanRECRUITING
The Role of Platelet Rich Plasma Injections in Cases of Stress Incontinence nanCOMPLETED
Treatment of Acral Vitiligo : Narrowband Ultraviolet-B and Microneedling With and Without Platelet Rich Plasma nanUNKNOWN
Platelet-rich Plasma for Thumb Carpometacarpal Joint Osteoarthritis nanCOMPLETED
Patient Satisfaction and Bone Gain Following Autogenous Particulate Sticky Bone Preparation With Xenograft Versus Without Xenograft for Grafting of Maxillary Anterior Knife Edge Ridge in Partially Edentulous Patients for Implant Placement nanUNKNOWN
Avapritinib in the Treatment of Unresectable or Recurrent Metastatic GIST Non-exon18 Mutations of PDGFRA nanRECRUITING
Effect of Platelet Rich Plasma on Healing of Operated Pilonidal Sinus by Open Method nanCOMPLETED
Management of Deep Retinal Capillary Ischemia by Electromagnetic Stimulation and Platelet- Rich Plasma nanCOMPLETED
Vocal Fold Injection by Platelet Rich Plasma nanNOT_YET_RECRUITING
The Effectiveness of Titanium-Prepared Platelet-Rich Fibrin on Angiogenic Biomarkers in Gingival Crevicular Fluid nanCOMPLETED
Cancer Fusion Hybrids and Desmoplasia nanUNKNOWN
Cellular Matrix Device for the Treatment of Mild to Moderate Knee Osteoarthritis nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a PDGFA binder may also engage these)

ProteinNameSimilarity
P28576 — 1.000 P28576 →
P20033 — 1.000 P20033 →
P34007 — 1.000 P34007 →
Q2KJ15 — 1.000 Q2KJ15 →
Q6Q7I7 — 1.000 Q6Q7I7 →
P13698 — 0.997 P13698 →
P01127 — 0.994 P01127 →
P12919 — 0.993 P12919 →
P01128 — 0.991 P01128 →
Q95229 — 0.991 Q95229 →
P31240 — 0.990 P31240 →
Q05028 — 0.985 Q05028 →
Q6J936 — 0.985 Q6J936 →
P16612 — 0.984 P16612 →
Q9PTQ2 — 0.983 Q9PTQ2 →
Q5BJ95 — 0.982 Q5BJ95 →
P0DW98 — 0.981 P0DW98 →
Q99PS1 — 0.981 Q99PS1 →
P97946 — 0.981 P97946 →
P50412 — 0.981 P50412 →
P27093 — 0.980 P27093 →
P09531 — 0.980 P09531 →
P20722 — 0.980 P20722 →
Q6X4U4 — 0.980 Q6X4U4 →
O40633 — 0.979 O40633 →
Q7T2X7 — 0.979 Q7T2X7 →
Q5XHC5 — 0.979 Q5XHC5 →
P67861 — 0.979 P67861 →
Q9MYV3 — 0.979 Q9MYV3 →
Q9YHT8 — 0.978 Q9YHT8 →