Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PRKCA | P17252 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3450330 | 0.83 | SLC1A5 (0.81) | SLC1A5ALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL3450327 | 0.83 | SLC1A5 (0.81) | SLC1A5ALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL24354992 | 0.77 | SLC1A5 (0.77) | SLC1A5ALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL17857748 | 0.76 | ALDH1A1 (0.65) | SLC1A5ALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL27890102 | 0.76 | ALDH1A1 (0.65) | SLC1A5ALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL12000806 | 0.75 | ALDH1A1 (0.74) | SLC1A5ALDH1A1ADRB2ADRB1ADRB3 | |
| Hydrochloric Acid SCHEMBL17837709 | 0.75 | ALDH1A1 (0.62) | SLC1A5ALDH1A1ADRB2ADRB1ADRB3 | |
| Hydrochloric Acid SCHEMBL17837705 | 0.75 | ALDH1A1 (0.62) | SLC1A5ALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL28117942 | 0.75 | ALDH1A1 (0.62) | SLC1A5ALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL20243012 | 0.74 | SLC1A5 (1.00) | SLC1A5ALDH1A1TDP1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0123442-B1 | IMPROVEMENTS IN OR RELATING TO A PROCESS FOR PRODUCING BETA-LACTAM COMPOUNDS | THE UNIVERSITY OF NOTRE DAME DU LAC (US) | 1988-06-15 | — | — | EP | disclosed |
| US-4675399-A | N-HYDROXY-2-AZETIDINONES; ACYLATION, SOLVOLYSIS | NOTRE DAME UNIVERSITY (US) | 1987-06-23 | — | — | US | disclosed |
| US-4565654-A | BETA-LACTAMASE ENZYME INHIBITORS | UNIVERSITY OF NOTRE DAME DU LAC (US) | 1986-01-21 | — | — | US | disclosed |
| EP-0123442-A1 | Improvements in or relating to a process for producing beta-lactam compounds | THE UNIVERSITY OF NOTRE DAME DU LAC (US) | 1984-10-31 | — | — | EP | disclosed |