Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | CCKBR | P32239 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CDC7 | O00311 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10652568 | 1.00 | BCHE (0.46) | BCHEACHELMNAELANETAAR1 | |
| SCHEMBL9496984 | 0.86 | ELANE (0.35) | ELANE | |
| SCHEMBL9496977 | 0.86 | ELANE (0.35) | ELANE | |
| SCHEMBL10346216 | 0.83 | GLA (0.42) | ELANEPOLB | |
| SCHEMBL10610532 | 0.82 | ELANE (0.36) | BCHEACHELMNAELANEMAPT | |
| SCHEMBL10654526 | 0.78 | BCHE (0.53) | BCHEACHELMNAELANETSHR | |
| SCHEMBL10654529 | 0.78 | BCHE (0.53) | BCHEACHELMNAELANETSHR | |
| SCHEMBL10654532 | 0.78 | BCHE (0.53) | BCHEACHELMNAELANETSHR | |
| SCHEMBL22406819 | 0.77 | ELANE (0.41) | ELANEMAPTPOLB | |
| SCHEMBL10382075 | 0.77 | ELANE (0.41) | ELANEMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0181581-B1 | BETA-AMINOTHIOL ESTER AND PROCESS FOR PREPARING THEREOF | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1988-07-13 | — | — | EP | disclosed |
| US-4728746-A | INTERMEDIATES FOR CARBAPENICILLINS | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1988-03-01 | — | — | US | disclosed |
| EP-0181581-A1 | beta-Aminothiol ester and process for preparing thereof | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1986-05-21 | — | — | EP | disclosed |