SCHEMBL9496984

SCHEMBL9496984

CC(O[Si](C)(C)C(C)(C)C)[C@@H]1C(=O)N[C@@H]1Cc1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.35
CTSD P07339 8/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9496977 1.00 ELANE (0.35) ELANECTSD
SCHEMBL10652568 0.86 BCHE (0.46) ELANE
SCHEMBL10652571 0.86 BCHE (0.46) ELANE
SCHEMBL10346216 0.82 GLA (0.42) ELANE
SCHEMBL10818399 0.81 ELANE (0.32) ELANE
SCHEMBL8017983 0.80 ELANE (0.33) ELANE
SCHEMBL9428568 0.80 ELANE (0.30) ELANE
SCHEMBL22581259 0.80
SCHEMBL22581258 0.80
SCHEMBL8441242 0.80 DDB1 (0.34) ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0304208-B1 CHEMICAL PROCESS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1993-05-12 EP disclosed
EP-0304208-A1 Chemical process IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1989-02-22 EP disclosed