SCHEMBL10653072

SCHEMBL10653072

Fc1ccc(C(F)OC2CCCCO2)c(F)c1F

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10585259 0.86 L3MBTL1 (0.32) IDO1L3MBTL1
SCHEMBL11090966 0.74
SCHEMBL10584850 0.70 IDO1 (0.33) IDO1L3MBTL1
SCHEMBL22494465 0.67 MEN1 (0.43) L3MBTL1
SCHEMBL16089742 0.67 SLC6A2 (0.49) IDO1L3MBTL1
SCHEMBL9433409 0.66 L3MBTL1 (0.31) L3MBTL1
SCHEMBL8979379 0.66 L3MBTL1 (0.31) L3MBTL1
SCHEMBL8979385 0.66 L3MBTL1 (0.31) L3MBTL1
SCHEMBL17145065 0.65 DPP4 (0.41) L3MBTL1
SCHEMBL7774635 0.65 SLC6A2 (0.39) L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0295839-A2 Pyrimidine derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-12-21 EP disclosed