Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 19/20 | 0.61 |
| ▸ | CNR2 | P34972 | 19/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5425933 | 0.90 | CNR2 (0.57) | CNR1CNR2 | |
| SCHEMBL69123 | 0.87 | CNR1 (0.58) | CNR1CNR2PTGS2 | |
| SCHEMBL31545799 | 0.87 | CNR1 (0.58) | CNR1CNR2PTGS2 | |
| SCHEMBL2027212 | 0.87 | CNR1 (0.58) | CNR1CNR2PTGS2 | |
| SCHEMBL23601974 | 0.86 | CNR2 (0.55) | CNR1CNR2 | |
| SCHEMBL5916439 | 0.85 | CNR1 (0.56) | CNR1CNR2PTGS2 | |
| SCHEMBL10653359 | 0.84 | CNR1 (0.64) | CNR1CNR2 | |
| SCHEMBL23802246 | 0.83 | CNR2 (0.50) | CNR1CNR2PTGS2 | |
| SCHEMBL10914094 | 0.83 | CNR2 (0.53) | CNR1CNR2 | |
| SCHEMBL10724501 | 0.83 | CNR2 (0.58) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0096480-B1 | PREPARATION OF 6A, 10A-TRANS-HEXAHYDRODIBENZOPYRANONES | ELI LILLY AND COMPANY (US) | 1988-09-28 | — | — | EP | claimed |
| EP-0096480-A2 | Preparation of 6a, 10a-trans-hexahydrodibenzopyranones | ELI LILLY AND COMPANY (US) | 1983-12-21 | — | — | EP | claimed |
| EP-0096480-B1 | PREPARATION OF 6A, 10A-TRANS-HEXAHYDRODIBENZOPYRANONES | ELI LILLY AND COMPANY (US) | 1988-09-28 | — | — | EP | disclosed |
| EP-0096480-A2 | Preparation of 6a, 10a-trans-hexahydrodibenzopyranones | ELI LILLY AND COMPANY (US) | 1983-12-21 | — | — | EP | disclosed |
| US-4395560-A | Preparation of 6a,10a-trans-hexahydrodibenzopyranones | ELI LILLY AND COMPANY (US) | 1983-07-26 | — | — | US | disclosed |