SCHEMBL5425933

SCHEMBL5425933

CCCCCCC(C)(C)c1cc(OC)cc(OC)c1

nearest known ligand 0.57

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 19/20 0.57
CNR1 P21554 15/20 0.57
TRPV1 Q8NER1 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23802246 0.93 CNR2 (0.50) CNR2CNR1TRPV1
SCHEMBL10724501 0.92 CNR2 (0.58) CNR2CNR1TRPV1
SCHEMBL23601974 0.92 CNR2 (0.55) CNR2CNR1TRPV1
SCHEMBL10653170 0.90 CNR1 (0.61) CNR2CNR1
SCHEMBL10914094 0.89 CNR2 (0.53) CNR2CNR1TRPV1
SCHEMBL23461341 0.88 CNR2 (0.48) CNR2CNR1TRPV1
SCHEMBL23461339 0.88 CNR2 (0.48) CNR2CNR1TRPV1
SCHEMBL17129735 0.85 ALDH1A1 (0.46) CNR2CNR1TRPV1
SCHEMBL23461342 0.84 CNR2 (0.52) CNR2CNR1TRPV1
SCHEMBL1171569 0.83 CNR2 (0.51) CNR2CNR1TRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4087410-A 5-(Tertiary alkyl) resorcinol preparation and intermediates therefor ELI LILLY AND COMPANY (US) 1978-05-02 US claimed
US-12612358-B2 Resorcinol-based compounds and uses thereof SUTTER BAY HOSPITALS (US) 2026-04-28 US disclosed
US-20250002435-A1 ARYLATED FENCHONE DERIVATIVES, COMPOSITIONS COMPRISING THEM, PROCESSES FOR THEIR PREPARATION AND USES THEREOF YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2025-01-02 US disclosed
EP-4412974-A1 ARYLATED FENCHONE DERIVATIVES, COMPOSITIONS COMPRISING THEM, PROCESSES FOR THEIR PREPARATION AND USES THEREOF Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. (IL) 2024-08-14 EP disclosed
US-20240059646-A1 RESORCINOL-BASED COMPOUNDS AND USES THEREOF ORGANIX INC. 2024-02-22 US disclosed
WO-2023058033-A1 ARYLATED FENCHONE DERIVATIVES, COMPOSITIONS COMPRISING THEM, PROCESSES FOR THEIR PREPARATION AND USES THEREOF YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2023-04-13 WO disclosed
WO-2022133058-A1 RESORCINOL-BASED COMPOUNDS AND USES THEREOF SUTTER BAY HOSPITALS (US) 2022-06-23 WO disclosed
WO-2022061461-A1 METHODS, PROCESSES, AND COMPOSITIONS FOR IMPROVED PREPARATION OF HU308 AND HU433 TETRA BIO-PHARMA INC. (CA) 2022-03-31 WO disclosed
US-20210198223-A1 METHODS AND COMPOSITIONS RELATING TO ULTRAPURE 5-(1,1-DIMETHYLHEPTYL)-RESORCINOL CORBUS PHARMACEUTICALS, INC. 2021-07-01 US disclosed
US-20190315669-A1 PROCESS FOR THE PREPARATION OF HU-910 AND CRYSTALLINE STRUCTURE THEREOF YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2019-10-17 US disclosed
US-20070155701-A1 KETO CANNABINOIDS WITH THERAPEUTIC INDICATIONS NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR 2007-07-05 US disclosed
US-20070060636-A1 High enantiomeric purity dexanabinol for pharmaceutical compositions PHARMOS CORPORATION 2007-03-15 US disclosed
US-20070060636-A1 High enantiomeric purity dexanabinol for pharmaceutical compositions PHARMOS CORPORATION 2007-03-15 US disclosed
US-20070060636-A1 High enantiomeric purity dexanabinol for pharmaceutical compositions PHARMOS CORPORATION 2007-03-15 US disclosed
EP-1567513-A2 HIGH ENANTIOMERIC PURITY DEXANABINOL FOR PHARMACEUTICAL COPOSITIONS PHARMOS CORPORATION (US) 2005-08-31 EP disclosed
WO-2004050011-A2 HIGH ENANTIOMERIC PURITY DEXANABINOL FOR PHARMACEUTICAL COPOSITIONS PHARMOS CORPORATION (US) 2004-06-17 WO disclosed
US-20040110827-A1 High enantiomeric purity dexanabinol for pharmaceutical compositions PHARMOS CORPORATION 2004-06-10 US disclosed
US-4707559-A 3-(6-ALKOXY-4-ALKYL-2-HYDROXYPHENYL)CYCLOHEXANOL DERIVATIVES YISSUM RESEARCH AND DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 1987-11-17 US disclosed
US-4131656-A Intermediates for 5-(tertiary alkyl) resorcinol preparation ELI LILLY AND COMPANY (US) 1978-12-26 US disclosed
US-4087410-A 5-(Tertiary alkyl) resorcinol preparation and intermediates therefor ELI LILLY AND COMPANY (US) 1978-05-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250002435-A1 ARYLATED FENCHONE DERIVATIVES, COMPOSITIONS COMPRISING THEM, PROCESSES FOR THEIR PREPARATION AND USES THEREOF CYP4F2, CYP4F8, CYP4F3 CNR2 732/4885CNR1 977/4885TRPV1 2590/4885
US-20210198223-A1 METHODS AND COMPOSITIONS RELATING TO ULTRAPURE 5-(1,1-DIMETHYLHEPTYL)-RESORCINOL CNR1, DHCR24, CNR2 CNR2 3/4885CNR1 1/4885TRPV1 627/4885
US-12612358-B2 Resorcinol-based compounds and uses thereof CARM1, MALT1, RCOR1 CNR2 397/4885CNR1 115/4885TRPV1 1827/4885
US-20070155701-A1 KETO CANNABINOIDS WITH THERAPEUTIC INDICATIONS CNR2, CNR1, FAAH CNR2 1/4885CNR1 2/4885TRPV1 7/4885
US-20070060636-A1 High enantiomeric purity dexanabinol for pharmaceutical compositions CNR2, CNR1, PDE8B CNR2 1/4885CNR1 2/4885TRPV1 143/4885
US-20240059646-A1 RESORCINOL-BASED COMPOUNDS AND USES THEREOF VHL, NQO1, HRAS CNR2 3315/4885CNR1 3278/4885TRPV1 3290/4885
US-20190315669-A1 PROCESS FOR THE PREPARATION OF HU-910 AND CRYSTALLINE STRUCTURE THEREOF HUWE1, SNRNP200, UACA CNR2 3253/4885CNR1 2723/4885TRPV1 4771/4885
US-20040110827-A1 High enantiomeric purity dexanabinol for pharmaceutical compositions CNR2, CNR1, PDE8B CNR2 1/4885CNR1 2/4885TRPV1 143/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.