Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL300185 | 0.82 | FFAR3 (0.43) | FFAR3ALDH1A1 | |
| SCHEMBL285140 | 0.82 | FFAR3 (0.43) | FFAR3ALDH1A1 | |
| SCHEMBL10768078 | 0.82 | — | — | |
| SCHEMBL28909413 | 0.82 | FFAR3 (0.43) | FFAR3ALDH1A1 | |
| SCHEMBL111807 | 0.82 | — | — | |
| SCHEMBL1196753 | 0.82 | — | — | |
| SCHEMBL4165623 | 0.78 | FFAR3 (0.40) | FFAR3ALDH1A1 | |
| Fluoride SCHEMBL11039310 | 0.78 | — | — | |
| Ethane SCHEMBL5581157 | 0.78 | FFAR3 (0.40) | FFAR3ALDH1A1 | |
| Methane SCHEMBL9008507 | 0.78 | FFAR3 (0.40) | FFAR3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0123543-B1 | LEUKOTRIENE ANTAGONISTS, THEIR PRODUCTION AND USE AND COMPOSITIONS CONTAINING THEM | MERCK FROSST CANADA INC. (CA) | 1988-02-03 | — | — | EP | disclosed |
| US-4609744-A | 4-oxo-benzopyran carboxylic acids | MERCK FROSST CANADA INC. (CA) | 1986-09-02 | — | — | US | disclosed |
| EP-0123543-A1 | Leukotriene antagonists, their production and use and compositions containing them | MERCK FROSST CANADA INC. (CA) | 1984-10-31 | — | — | EP | disclosed |