Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10650323 | 0.82 | HSD17B10 (0.49) | CA2HSD17B10POLBTDP1KDM4E | |
| SCHEMBL3626456 | 0.81 | CA2 (0.62) | CA2HSD17B10POLBTDP1KDM4E | |
| Hydrochloric Acid SCHEMBL10770897 | 0.80 | CA2 (0.61) | CA2HSD17B10POLBTDP1KDM4E | |
| SCHEMBL7269675 | 0.79 | CA2 (0.40) | CA2BCHEACHENOX1IDO1 | |
| SCHEMBL10507960 | 0.75 | POLB (0.61) | POLBTDP1IDO1SMN1; SMN2KMT2A | |
| SCHEMBL6570475 | 0.70 | CA2 (1.00) | CA2HSD17B10POLBTDP1KDM4E | |
| SCHEMBL7281597 | 0.70 | HSD17B10 (0.52) | CA2HSD17B10POLBTDP1KDM4E | |
| SCHEMBL2362237 | 0.70 | HSD17B10 (0.49) | CA2HSD17B10POLBTDP1KDM4E | |
| SCHEMBL7278586 | 0.70 | MAPT (0.62) | CA2HSD17B10POLBTDP1KDM4E | |
| SCHEMBL7463659 | 0.68 | BRD4 (0.51) | ALOX15RECQLTSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4755509-A | Heterocyclic aldose reductase inhibitors and methods of using them | Carbipem (FR) | 1988-07-05 | — | — | US | disclosed |