Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10649115 | 0.81 | MAPT (0.46) | HSD17B10GLAKDM4ETDP1USP2 | |
| SCHEMBL7278586 | 0.78 | MAPT (0.62) | HSD17B10GLAKDM4ETDP1USP2 | |
| SCHEMBL3626456 | 0.77 | CA2 (0.62) | HSD17B10GLAKDM4ETDP1USP2 | |
| Hydrochloric Acid SCHEMBL10770897 | 0.76 | CA2 (0.61) | HSD17B10GLAKDM4ETDP1USP2 | |
| SCHEMBL7278853 | 0.75 | HSD17B10 (0.46) | HSD17B10GLAKDM4ETDP1USP2 | |
| SCHEMBL28768922 | 0.73 | HSD17B10 (0.53) | HSD17B10GLAKDM4ETDP1USP2 | |
| SCHEMBL2362237 | 0.72 | HSD17B10 (0.49) | HSD17B10GLAKDM4ETDP1USP2 | |
| SCHEMBL10650323 | 0.72 | HSD17B10 (0.49) | HSD17B10GLAKDM4ETDP1USP2 | |
| SCHEMBL7281597 | 0.72 | HSD17B10 (0.52) | HSD17B10GLAKDM4ETDP1USP2 | |
| SCHEMBL17634130 | 0.72 | MAPT (0.66) | HSD17B10GLAKDM4ETDP1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4755509-A | Heterocyclic aldose reductase inhibitors and methods of using them | Carbipem (FR) | 1988-07-05 | — | — | US | disclosed |