Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.57 |
| ▸ | PGR | P06401 | 1/20 | 0.57 |
| ▸ | HTR1A | P08908 | 1/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.57 |
| ▸ | AR | P10275 | 1/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.57 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | NOD1 | Q9Y239 | 8/20 | 0.56 |
| ▸ | GLP1R | P43220 | 8/20 | 0.55 |
| ▸ | TLR2 | O60603 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pimelautide SCHEMBL28126753 | 0.92 | NOD1 (0.65) | ESR1PGRHTR1AADORA3AR | |
| Pimelautide SCHEMBL444469 | 0.92 | NOD1 (0.65) | ESR1PGRHTR1AADORA3AR | |
| SCHEMBL21389122 | 0.84 | NOD1 (0.62) | ESR1PGRHTR1AADORA3AR | |
| SCHEMBL24795872 | 0.84 | NOD1 (0.65) | NOD1GLP1REPHX2SLC6A5 | |
| SCHEMBL21549155 | 0.84 | NOD1 (0.65) | NOD1GLP1REPHX2SLC6A5 | |
| SCHEMBL21389192 | 0.83 | NOD1 (0.64) | NOD1GLP1REPHX2SLC6A5 | |
| SCHEMBL25878526 | 0.82 | NOD1 (0.63) | NOD1GLP1REPHX2SLC6A5 | |
| SCHEMBL25877865 | 0.82 | NOD1 (0.63) | NOD1GLP1REPHX2SLC6A5 | |
| SCHEMBL15084766 | 0.82 | NOD1 (0.63) | NOD1GLP1RTLR2EPHX2SLC6A5 | |
| SCHEMBL9785097 | 0.81 | NOD1 (0.71) | NOD1GLP1RSLC6A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4742048-A | Tetrapeptides and pentapeptides, their preparation and compositions containing them | RHONE-POULENC INDUSTRIES (FR) | 1988-05-03 | — | — | US | disclosed |