Dimethylamine

Dimethylamine

SCHEMBL10653757

CNC.O=C(O)N(c1ccccc1)c1ccccc1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 3/20 0.58
ALDH1A1 P00352 4/20 0.48
KMT2A Q03164 4/20 0.48
NPC1 O15118 1/20 0.48
POLB P06746 1/20 0.48
HTT P42858 1/20 0.48
RAB9A P51151 1/20 0.48
L3MBTL1 Q9Y468 3/20 0.47
ATM Q13315 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
TRPM8 Q7Z2W7 2/20 0.44
GLA P06280 1/20 0.43
TSHR P16473 1/20 0.43
MEN1 O00255 3/20 0.43
NR3C2 P08235 1/20 0.42
LMNA P02545 1/20 0.42
CHRM4 P08173 1/20 0.42
CHRM3 P20309 1/20 0.42
GAA P10253 1/20 0.41
MAPT P10636 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19778 0.90 NPSR1 (0.70) NPSR1ALDH1A1KMT2ANPC1POLB
Methylamine SCHEMBL10655180 0.88 NPSR1 (0.61) NPSR1ALDH1A1KMT2ANPC1POLB
Bromide SCHEMBL31210017 0.87 NPSR1 (0.67) NPSR1ALDH1A1KMT2ANPC1POLB
Hydrochloric Acid SCHEMBL5094831 0.87 NPSR1 (0.67) NPSR1ALDH1A1KMT2ANPC1POLB
SCHEMBL28228964 0.83 NPSR1 (0.61) NPSR1ALDH1A1KMT2ANPC1POLB
SCHEMBL27979506 0.83 NPSR1 (0.61) NPSR1ALDH1A1KMT2ANPC1POLB
Carbamic Acid SCHEMBL11376840 0.83 NPSR1 (0.61) NPSR1ALDH1A1KMT2ANPC1POLB
Diphenylamine SCHEMBL10650342 0.82 NPSR1 (0.54) NPSR1ALDH1A1KMT2ANPC1POLB
SCHEMBL2091758 0.82 TRPM8 (0.56) NPSR1ALDH1A1KMT2ANPC1POLB
Carbamic Acid SCHEMBL10488831 0.81 NPSR1 (0.58) NPSR1ALDH1A1KMT2ANPC1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0273456-A2 Vapor phase alcoholysis of aminosilanes and carbamatosilanes UNION CARBIDE CORPORATION (US) 1988-07-06 EP disclosed
US-4730074-A Vapor phase alcoholysis of aminosilanes and carbamatosilanes UNION CARBIDE CORPORATION (US) 1988-03-08 US disclosed
EP-0098912-B1 PROCESS FOR THE PREPARATION OF ALKOXYHYDRIDOSILANES UNION CARBIDE CORPORATION (US) 1986-04-23 EP disclosed
EP-0098911-B1 IMPROVED PROCESS FOR THE PREPARATION OF OXIMATOHYDRIDOSILANES AND AMINOXYHYDRIDOSILANES UNION CARBIDE CORPORATION (US) 1986-04-16 EP disclosed
EP-0098911-A1 Improved process for the preparation of oximatohydridosilanes and aminoxyhydridosilanes UNION CARBIDE CORPORATION (US) 1984-01-25 EP disclosed
EP-0098912-A1 Process for the preparation of alkoxyhydridosilanes UNION CARBIDE CORPORATION (US) 1984-01-25 EP disclosed
US-4395564-A REACTING AN ALCOHOL WITH SILYL-AMINE UNION CARBIDE CORPORATION (US) 1983-07-26 US disclosed
US-4384131-A Process for the preparation of oximatohydridosilanes and aminoxyhydridosilanes UNION CARBIDE CORPORATION (US) 1983-05-17 US disclosed