SCHEMBL10654027

SCHEMBL10654027

CC(C)COCCOCC(CN)CCCN

nearest known ligand 0.49

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.49
ALDH1A1 P00352 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10652745 0.85 CYP3A4 (0.49) CYP3A4ALDH1A1TDP1HTT
SCHEMBL10649961 0.85 CYP3A4 (0.53) CYP3A4ALDH1A1TDP1HTT
SCHEMBL9713676 0.82 CYP3A4 (0.59) CYP3A4ALDH1A1TDP1HTT
SCHEMBL10650582 0.81 CYP3A4 (0.64) CYP3A4ALDH1A1TDP1HTT
SCHEMBL9713860 0.81 CYP3A4 (0.68) CYP3A4ALDH1A1TDP1HTT
SCHEMBL10649211 0.78 CYP3A4 (0.64) CYP3A4ALDH1A1TDP1HTT
SCHEMBL10648852 0.78 CYP3A4 (0.64) CYP3A4ALDH1A1TDP1HTT
SCHEMBL10652917 0.78 CYP3A4 (0.48) CYP3A4ALDH1A1TDP1
SCHEMBL9714108 0.77 CYP3A4 (0.42) CYP3A4ALDH1A1TDP1
SCHEMBL234207 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4748226-A Method of preparation of novel 2-(alkoxymethyl)-pentane-1,5-diisocyanates, 2-(alkoxymethyl)-pentane-1,5-diurethanes, and 2-(alkoxymethyl)-pentane-1,5-dicarbamic acid chlorides and their uses BASF AKTIENGESELLSCHAFT (DE) 1988-05-31 US disclosed