SCHEMBL10654063

SCHEMBL10654063

COc1ccc(C2=NN(c3ccccc3)C(c3ccc(N)cc3)C2)cc1

nearest known ligand 0.91

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.91
KMT2A Q03164 5/20 0.91
KDM4E B2RXH2 3/20 0.91
ALDH1A1 P00352 3/20 0.91
MAPT P10636 3/20 0.91
LMNA P02545 1/20 0.91
EGFR P00533 4/20 0.73
ERBB2 P04626 2/20 0.73
L3MBTL1 Q9Y468 5/20 0.71
ATM Q13315 4/20 0.71
RAB9A P51151 1/20 0.71
PDE5A O76074 4/20 0.67
GLA P06280 2/20 0.67
GAA P10253 2/20 0.67
NPSR1 Q6W5P4 2/20 0.67
POLB P06746 1/20 0.67
CDC42 P60953 1/20 0.67
CA1 P00915 1/20 0.67
CA2 P00918 1/20 0.67
USP2 O75604 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11123578 0.94 KDM4E (0.88) MEN1KMT2AKDM4EALDH1A1MAPT
SCHEMBL10362296 0.94 EGFR (0.81) MEN1KMT2AKDM4EALDH1A1MAPT
SCHEMBL9514571 0.91 MEN1 (0.78) MEN1KMT2AKDM4EALDH1A1MAPT
SCHEMBL8171663 0.91 MEN1 (0.83) MEN1KMT2AKDM4EALDH1A1MAPT
SCHEMBL11205361 0.89 EGFR (0.74) MEN1KMT2AKDM4EALDH1A1MAPT
SCHEMBL11210797 0.89 EGFR (0.74) MEN1KMT2AKDM4EALDH1A1MAPT
SCHEMBL15301347 0.89 MEN1 (0.82) MEN1KMT2AKDM4EALDH1A1MAPT
SCHEMBL15301136 0.89 KDM4E (0.88) MEN1KMT2AKDM4EALDH1A1MAPT
SCHEMBL15377485 0.88 EGFR (0.73) MEN1KMT2AKDM4EALDH1A1MAPT
SCHEMBL15377475 0.88 EGFR (0.73) MEN1KMT2AKDM4EALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4719174-A USING ABSORPTIVE COMPOUND WHICH RELEASES ELECTRONS UPON EXPOSURE FUJI PHOTO FILM CO., LTD. (JP) 1988-01-12 US disclosed
US-4607006-A Silver halide photographic light-sensitive material containing non-spectral sensitizing electron donative silver halide adsorptive compound FUJI PHOTO FILM CO., LTD. (JP) 1986-08-19 US disclosed